Results 151 to 160 of about 16,004,083 (304)

Whose security? whose rights? : governance and human rights in international cooperation; a CCIC / reality of aid conference and the launch of the reality of aid 2004 report, May 28-29, 2004, conference report

open access: yes, 2004
French version available in IDRC Digital Library: Sécurité pour qui? les droits de qui? : la gouvernance et les droits de la personne dans le champ de la coopération internationale; un congrès de CCCI sur le bilan de l'aide, publication du rapport Bilan ...

core  

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao   +8 more
wiley   +1 more source

Scarperation : an empirical inquiry into the role of scarcity in fostering cooperation between international river riparians [PDF]

open access: yes
The environment and security literature has argued that freshwater scarcity often leads to inter-state conflict, and possibly acute violence. The contention, however, ignores the long history of hydro-political cooperation exemplified by hundreds of ...
Dinar, Shlomi   +2 more
core  

Curvature‐Controlled Field Effect Enables Thermal Localization for Low‐Temperature C─F Bond Activation

open access: yesAdvanced Science, EarlyView.
High‐curvature γ‐Al2O3 nanoneedles concentrate heat into nanoscale hotspots under identical external heating, amplifying local temperature and accelerating CF4 decomposition. By linking curvature‐induced thermal localization to lower apparent activation barriers and enhanced intermediate formation, this work reveals geometry as a powerful design ...
Hang Zhang   +12 more
wiley   +1 more source

Long-Standing International Cooperation in Parasitology Research: A Summary of 35 Years of Activities in the Bolivian Chaco. [PDF]

open access: yesTrop Med Infect Dis, 2022
Gabrielli S   +17 more
europepmc   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang   +11 more
wiley   +1 more source

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