Results 231 to 240 of about 901,705 (329)

Safety and Efficacy of the NMDA‐2b‐Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder

Clinical Pharmacology &Therapeutics, EarlyView.
Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre, Gerard Sanacora, David P. Walling, Elan A. Cohen, Shishuka Malhotra, Holger Rosenbrock, Manuela Schmitz, Andreas Scholz, Sigurd D. Süssmuth, Franco De Crescenzo   +9 more
wiley   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang, Kevin J. O'Leary, Edith A. Nutescu, Matthew Jack, Thomas Chen, Gregory W. Ruhnke, James C. Lee, David George, Larry K. House, Randall Knoebel, Luke V. Rasmussen, Seth Hartman, Anish Choksi, Kiang‐Teck J. Yeo, Minoli A. Perera, Mark J. Ratain, David O. Meltzer, Peter H. O'Donnell   +17 more
wiley   +1 more source

IOC/IASC/IHO Editorial Board for the International Bathymetric Chart of the Arctic Ocean, report of meeting: Dartmouth, Canada; June 24, 1999

, 2000
R Macnab, Mike Jones
openalex   +1 more source

They entered without any rumor: human rights in the Belgian legal periodicals [PDF]

, 2012
Vandenbogaerde, Sebastiaan
core  

UGT1A1 and Sacituzumab Govitecan Toxicity: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Sacituzumab govitecan (SG), a humanized antibody‐drug conjugate, enables intra‐tumor delivery of SN‐38, the active metabolite of irinotecan, with the aim of increasing efficacy. SN‐38 is predominantly inactivated by the polymorphically expressed uridine diphosphate glucuronosyltransferase 1A1 (UGT1AA) where reduced activity can lead to toxicity.
Cinzia Dello Russo, Innocent Gerald Asiimwe, Sudeep Pushpakom, Carlo Palmieri, Munir Pirmohamed   +4 more
wiley   +1 more source

<i>Healthcare</i> Reloaded: Announcing the New Aims and Scope of <i>Healthcare</i>. [PDF]

Healthcare (Basel)
Evangelista LS.
europepmc   +1 more source

Foreword in International Encyclopedia of Dance [PDF]

, 1998
Carter, Curtis
core   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Investigating Factors for an Inclusive Workforce for Women in the Logistics and Supply Chain Industry

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study seeks to identify and analyze the major factors that contribute to an inclusive workforce for women in the area of logistics and supply chain. It further addresses the need for gender diversity and inclusivity in a traditionally male‐dominated field by adopting a human‐centric approach.
Vernika Agarwal, Shefali Srivastava, Ashish Dwivedi, Sanjoy Kumar Paul, Anchal Patil   +4 more
wiley   +1 more source

Memory words - in memorium. [PDF]

Int J Circumpolar Health
Kallenborn R, Mulvad G, Rautio A, Reiersen LO, Sonne C, Vorkamp K, Weihe P, Andreasen I.   +7 more
europepmc   +1 more source