Results 51 to 60 of about 6,148,990 (307)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Fall 2007, Hamilton receives International Excellence Award [PDF]
, 2007 Professor Larry Hamilton, Department of Sociology, was named recipient of the 2007-08 UNH Award for Excellence in International ...
Center for International Education
core +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Cooperation vs. Deliberation: CMC and the Problem of Argument in International Distance Education
International Review of Research in Open and Distributed Learning, 2002 The idea that Internet-based distance education offers the potential to globalize higher education has not been matched by significant interest in the pedagogical and methodological issues at stake.
Michael Davis, Albert Rouzie
doaj
Expert Journal of Marketing, 2022 Determining the return on investment of international education has always been complicated and the COVID-19 pandemic makes it even more so, justifying the need for prospective international students to reach out to their social environs.
Huda MAULANA
doaj
UNH Faculty Abroad Series, Fall 2011 [PDF]
, 2011 Eun Kyeong Cho UNH Department of Education September 27, 2011 Early Childhood Education and Cross-Cultural Collaboration: Lessons from South Korea Alynna Lyon UNH Department of Political Science October 18, 2011 Strategic Humanitarian Intervention ...
Center for International Education
core +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
UNH Faculty Abroad Series; Spring 2011 [PDF]
, 2011 Ruth Varner UNH Earth Systems Research Center February 17, 2011 Listening for Climate Change North of the Artic Circle Julie Bryce UNH Department of Earth Sciences March 24, 2011 Snapshots of Carbonated Deep Earth: Geochemical Adventures in Italy ...
Center for International Education
core +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source