Results 191 to 200 of about 826,516 (353)

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Publishing in the Era of Artificial Intelligence: What Do Medical Research Journals Expect? [PDF]

Cureus
Afzal I, Radha S.
europepmc   +1 more source

International Financial Reporting Standards

IOSR Journal of Business and Management, 2016
openaire   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Hospital Accreditation Governance in Afghanistan: Challenges and Solutions. [PDF]

J Healthc Leadersh
Massror AQ, Mosadeghrad AM, Dargahi H, Jaafaripooyan E, Azarakhsh AH.   +4 more
europepmc   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

From data to decisions: Toward a Biodiversity Monitoring Standards Framework. [PDF]

Proc Natl Acad Sci U S A
Gonzalez A, August T, Bailey S, Bobiwash K, Boersch-Supan PH, Burgess ND, Daru BH, Elphick CS, Freckleton RP, Frick WF, Hughes AC, Isaac NJB, Jones JPG, Lambertini M, Mac Aodha O, Madhavapeddy A, Milner-Gulland EJ, Purvis A, Salafsky N, Sutherland WJ, Tanshi I, Vijay V, Woodard SH, Williams DR.   +23 more
europepmc   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

Do ESG Frameworks Capture Corporate Health Impacts? An Analysis of the Food and Beverage Industry. [PDF]

Int J Environ Res Public Health
Burgess R, Chen K, Kim SJ, Dharia N, Lin C, Srebotnjak T, Grierson L, Freudenberg N, Esty DC, Ransome Y.   +9 more
europepmc   +1 more source

The Relationship Between Financial Reporting and Sustainability Report. The Exposure Draft: IFRS S1 General Requirement for Disclosure of Sustainability-Related Financial Information (From International Sustainability Standard Board) Overcomes the Duality of External Corporate Disclosure

, 2022
Maria Silvia Avi
openalex   +2 more sources