Results 71 to 80 of about 16,887,669 (412)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

BRICS health and tuberculosis control collaborations during an era of global health

open access: yesMedicine Anthropology Theory, 2015
In this think piece, I examine the difference introduced by BRICS (Brazil, Russia, India, China, and South Africa) health collaborations in an era of global health.
Emilio Dirlikov
doaj   +1 more source

Rebuilding health care in Iraq [PDF]

open access: yes, 2004
The effects of three wars within 25 years, a decade of international sanctions, and a brutal regime have had tragic consequences on Iraq’s health system and on the health of the Iraqi people.
Furber, A.S., Johnstone, P.
core   +2 more sources

Standards of Care for the Health of Transgender and Gender Diverse People, Version 8

open access: yesInternational Journal of Transgender Health, 2022
Background: Transgender healthcare is a rapidly evolving interdisciplinary field. In the last decade, there has been an unprecedented increase in the number and visibility of transgender and gender diverse (TGD) people seeking support and gender ...
E. Coleman   +118 more
semanticscholar   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

English-based Pediatric Emergency Medicine Software Improves Physician Test Performance on Common Pediatric Emergencies: A Multicenter Study in Vietnam

open access: yesWestern Journal of Emergency Medicine, 2013
Introduction: Global health agencies and the Vietnam Ministry of Health have identified pediatric emergency care and health information technology as high priority goals. Clinical decision support (CDS) software provides physicians with access to current
Michelle Lin   +8 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Salud internacional: el nuevo desafío para la educación de enfermería International health: a new challenge to nursing education

open access: yesRevista Latino-Americana de Enfermagem, 1998
Para identificar las actividades de salud internacional (SI) en escuelas de enfermería y analizarlas en forma preliminar, se utilizó una muestra de 110 escuelas norteamericanas y, paralelamente, se enviaron cuestionarios a 4 escuelas latinoamericanas y a
Maria da Gloria Miotto Wright   +3 more
doaj   +1 more source

Ebola, Zika and the International Health Regulations – implications for Port Health Preparedness

open access: yesGlobalization and Health, 2016
BackgroundThe outbreak of Ebola Virus Disease in West Africa in 2014-2015 was unprecedented in terms of its scale and consequence.  This, together with the emergence of Zika virus as a Public Health Emergency of International Concern in 2016, has again ...
R. Glynn   +2 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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