Results 81 to 90 of about 29,624,517 (312)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Kelevan : health and safety guide

, 1987
Companion volume to: Environmental health criteria ; 66Published by the World Health Organization for the International Programme on Chemical Safety20 ...
World Health Organization, International Programme on Chemical Safety   +1 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Trichlorfon : health and safety guide

, 1991
Published by the World Health Organization for the International Programme on Chemical SafetyCompanion volume to: Environmental health criteria ; 13241 ...
World Health Organization, International Programme on Chemical Safety   +1 more
core  

The Maturation of the International Health Crisis Response: The Polish Typhus Epidemic of 1916–1923 Compared to the African Ebola Virus Disease Epidemic of 2013–2016: Part I, the Polish Epidemic

Epidemiologia
Poland suffered an epidemic of louse-borne typhus from 1916–1923, with 400,000 cases and more than 130,000 deaths. The causative factors were depressed economic conditions and a refugee crisis that engulfed Poland after World War I.
Gregory M. Anstead
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Chlordane : health and safety guide

, 1988
Companion volume to: Environmental health criteria ; 34Published by the World Health Organization for the International Programme on Chemical Safety35 ...
World Health Organization, International Programme on Chemical Safety   +1 more
core  

Perfil del viajero internacional: el trabajo como motivo de viaje

Medicina y Seguridad del Trabajo
Objetivos: describir la población a estudio y comparar el motivo de viaje laboral con el motivo turístico y con la Visita de Amigos o Familiares (VFRs) para estimar si existe un perfil de riesgo diferente.
M.ª Belén Robles García
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Endosulfan : health and safety guide

, 1988
Companion volume to: Environmental health criteria ; 40Published by the World Health Organization for the International Programme on Chemical Safety39 ...
World Health Organization, International Programme on Chemical Safety   +1 more
core