Results 51 to 60 of about 2,490,434 (301)

‘Framing the project’ of international human rights law: Reflections on the dysfunctional ‘family’ of the Universal Declaration [PDF]

open access: yes, 2012
Full text embargoed until November 2013.The task of ‘framing the project’ of international human rights law is daunting to say the least. First, there is the sheer enormity and complexity of the international human rights law ‘project’: adequately ...
Amin Al-Midani   +36 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Human Rights in Global Health Governance [PDF]

open access: yes, 2018
Human rights frame global health governance. In codifying a normative foundation for global governance in the aftermath of World War II, states came together under the auspices of an emergent United Nations (UN) to develop human rights under ...
Gostin, Lawrence O.   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Managing Risk: International Labor and Human Rights [PDF]

open access: yes, 2018
A corporate leader’s nightmare scenario: waking to the news of the collapse of a factory manufacturing the company’s products, reading headlines about the company’s involvement in child labor abuses, or learning of work stoppages at supplier plants over ...
Baker & McKenzie
core   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

The integration of the asylum seekers and the state of permanent emergency of the immigrants in Calabria [PDF]

open access: yesGlasnik Etnografskog Instituta SANU, 2014
This paper aims to analyze the situation of the asylum seekers and the economic immigrants starting from an historic and legislative summary of the immigration in Italy. The case study concerns the situation in Calabria, Southern Italy.
Riso Patrizia, Mazzilli Caterina
doaj   +1 more source

International Human Rights: Islam\u27s Friend or Foe? Algeria as an Example of the Compatibility of International Human Rights Regarding Women\u27s Equality and Islamic Law [PDF]

open access: yes, 1996
Part I of this Note briefly discusses the development of International Human Rights Law as embodied in international covenants today. Part I also discusses Islamic law, the traditional role of women under Islamic law and culture, Algeria\u27s ...
Entelis, Joelle
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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