Results 91 to 100 of about 3,266,878 (301)

Political Institutions, State Capabilities and Public Policy - International Evidence [PDF]

open access: yes
This paper introduces preliminary evidence from a cross-country database of policy characteristics and potential uses of that database. While most databases have emphasized either the content of policies (e.g., size of government deficits) or countries ...
Carlos Scartascini   +2 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

International Law and the American National Interest [PDF]

open access: yes, 2000
There are those, John Bolton and Paul Stephan among them, who worry that international law poses something of a threat to the US national interest. They argue that the United States should disengage from international law and international institutions ...
Byers, Michael
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Parenting style and child mental health at preschool age: evidence from rural China

open access: yesBMC Psychiatry
Background Mental health problems among children at preschool age are a common issue across the world. As shown in literature, a caregiver’s parenting style can play a critical role in child development.
Lei Wang, Jing Tian, Scott Rozelle
doaj   +1 more source

What Works (And Does Not Work) in Industrial Relations System Change to Promote Effective Workplace Participation? France, 1981 and Thereafter [PDF]

open access: yes, 1994
Paper presented to International Evidence: Worker-Management Institutions and Economic Performance Conference, U.S. Commission on the Future of Worker-Management Relations.Paper_Rojot_France.pdf: 257 downloads, before Oct.
Rojot, Jacques
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Towards a Dynamic Model of the Interplay Between International Institutions [PDF]

open access: yes
International institutions increasingly affect each other’s development, maintenance and effectiveness. Research so far has merely focused on the issue of effectiveness and broader consequences. The paper argues firstly that theoretical progress could be
Howard Loewen
core  

Human security as ‘Ethnic Security’ in Kosovo [PDF]

open access: yes, 2010
In Kosovo, the concept of human security is invoked in a three-fold manner. First of all, the international community has applied human security for the purpose of maintaining a fragile peace and stability in Kosovo.
Beha, Adem, Visoka, Gëzim
core  

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