Results 71 to 80 of about 3,266,878 (301)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Institutional Change and Compliance in Forest Landscape Restoration Governance: Insights from the Western Highlands of Cameroon

open access: yesJournal of Land Use Science
The debate regarding whether, in sub-Saharan Africa, exogenous1 and endogenous institutions2 have witnessed significant changes to facilitate contemporary Forest Landscape Restoration (FLR) processes remains inconclusive.
Raphael Owusu   +2 more
doaj   +1 more source

Wage subsidies and international trade: when does policy coordination pay? [PDF]

open access: yes, 2010
National labour market institutions interact across national boundaries when product markets are global. Labour market policies can thus entail spill-overs, a fact widely ignored in the academic literature.
Braun, S., Spielmann, Christian
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Analysis of antibiotic use, biosecurity and mortality in semi-intensive broiler farms in Kenya

open access: yesBMC Veterinary Research
The indiscriminate use of antibiotics in food-producing animals contributes to antimicrobial resistance (AMR), posing a global threat. Understanding the factors associated with antibiotic use is critical to combat resistance while maintaining animal ...
Naomi P. Kemunto   +7 more
doaj   +1 more source

The impact of international institutions on Brussels: a multi‑criteria analysis approach

open access: yesBrussels Studies, 2008
This paper develops an integrated assessment framework for costs and benefits related to the presence of international institutions in Brussels, Belgium.
Eric Corijn   +3 more
doaj   +1 more source

Risk sharing, finance and institutions in international portfolios [PDF]

open access: yes
We show that international consumption risk sharing is significantly improved by capital flows, especially portfolio investment. Concomitantly, we show that poor institutions hamper risk sharing, but to an extent that decreases with openness.
Fratzscher, Marcel, Imbs, Jean
core  

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