Results 91 to 100 of about 1,193,453 (300)

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Configurations of Extremal Even Unimodular Lattices

, 2007
We extend the results of Ozeki on the configurations of extremal even unimodular lattices. Specifically, we show that if L is such a lattice of rank 56, 72, or 96, then L is generated by its minimal-norm vectors.Comment: 8 pages. To appear, International
SCOTT DUKE KOMINERS, Venkov B. B., Venkov B. B., Vilenkin N. J.   +3 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Health and Humanitarian Assistance: Towards an Integrated Norm under International Law

Tilburg Law Review, 2013
This contribution assesses how a set of health-related norms under international law and ethics apply to situations where humanitarian assistance is provided.
Brigit Toebes
doaj   +1 more source

Motivational Internalism and Normativity

Etyka, 2017
Motivational internalism is a view about the connection between motivation and moral judgment. The debate over internalism has long focused on establishing the nature of the connection between moral judgment and motivation. In this paper I argue that recent studies regarding personality disorders such as psychopathy and VM damage, which have been ...
openaire   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Simulations of one-flavor QCD at finite temperature by RHMC [PDF]

, 2007
We simulate one-flavor QCD with standard Wilson fermions at finite temperature by the rational hybrid Monte Carlo algorithm. In the heavy quark region when we decrease the quark mass there is an endpoint which terminates the first order phase transition.
Nakamura, Atsushi, Takaishi, Tetsuya
core   +1 more source

A First Derivative Potts Model for Segmentation and Denoising Using ILP

, 2018
Unsupervised image segmentation and denoising are two fundamental tasks in image processing. Usually, graph based models such as multicut are used for segmentation and variational models are employed for denoising. Our approach addresses both problems at
D Bertsimas, Jörg Hendrik Kappes, M Storath, RB Potts   +3 more
core   +1 more source