Az apixaban hatékonysága és biztonságossága a warfarinhoz képest a terápiás tartományban töltött idő függvényében [Efficacy and safety of apixaban compared with warfarin regarding time within the therapeutic range] [PDF]
Prevention of thromboembolism by lifelong anticoagulation is an important therapeutic goal in patients with atrial fibrillation according to recent guidelines.
Havasi Kálmán
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Introduction The international normalized ratio (INR) is a biomarker of coagulopathy. The objective of this study was to assess the relationship between the INR and clinical outcomes in patients with large vessel occlusion (LVO) stroke who received ...
Yapeng Guo+10 more
doaj +1 more source
THE INITIAL STAGE OF TESTING THE DEVELOPED APPARATUS TO DETERMINE THE INTERNATIONAL NORMALIZED RATIO
Prothrombin time (PTT) is a laboratory indicator that allows to evaluate the external pathway of blood coagulation (activity of factors I, II, V, VII and X). An INR indicator was introduced to standardize the results of the PTV test. INR = (patient’s PTT/
Natalya Valeryevna Aksyutina+10 more
doaj +1 more source
AIM To study in patients performing international normalized ratio (INR) self-control the efficacy and safety of an INR target range of 1.6-2.1 for aortic valve replacement (AVR) and 2.0-2.5 for mitral valve replacement (MVR) or double valve replacement (
H. Koertke+10 more
semanticscholar +1 more source
Does routine repeat testing of critical laboratory values improve their accuracy? [PDF]
Background: Routine repeat testing of critical laboratory values is very common these days to increase their accuracy and to avoid reporting false or infeasible results. We figure that repeat testing of critical laboratory values has any benefits or not.
Kadivar, M.+3 more
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Exact buckling analysis of composite elastic columns including multiple delamination and transverse shear [PDF]
The exact analytical solution of buckling in beams with multiple delaminations is presented. In order to investigate analytically the influence of axial and shear strains on buckling loads, the geometrically exact beam theory is employed with no ...
Planinc, Igor+3 more
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BACKGROUND Anticoagulation management is difficult in chronic kidney disease, with frequent supratherapeutic international normalized ratios (INRs ≥ 4) increasing hemorrhagic risk.
N. Limdi+7 more
semanticscholar +1 more source
Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
A. John Camm+72 more
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Laboratory Reporting of the International Normalized Ratio: Progress and Problems
Abstract Context.—The international normalized ratio (INR) is widely used to monitor oral anticoagulation and to evaluate patients with coagulation disorders. Objective.—To examine the variability of the performance and reporting of the INR and to evaluate laboratory calculation of the INR.
Mark T. Cunningham+9 more
openaire +3 more sources
Does warfarin prevent venous thromboembolic events in aPL-positive patients? [PDF]
Yes, warfarin is effective in the secondary prevention of venous thromboembolic events (VTEs) for patients positive for lupus anticoagulant or anticardiolipin antibody (also known as antiphospholipid antibodies [aPL]) (strength of recommendation [SOR]: B,
Jamieson, Barbara, Mazzone, Michael F.
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