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A Microfluidic Digital Shutter of Liquid–Liquid Interface for Fabrication of Multifaceted Hydrogel Microfiber Structure

open access: yesAdvanced Science, EarlyView.
A programmable passive digital shutter based on multiphase liquid–liquid interface dynamics is introduced for precise fabrication of hydrogel microfibers. By modulating the shutter operation, microfibers with tunable geometry—including linear, helical, tadpole‐like, and spherical forms—are produced.
Dongrui Zhang   +14 more
wiley   +1 more source
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Fiddleheads and the International Normalized Ratio

New England Journal of Medicine, 1998
To the Editor: Many drugs and foods affect the response to oral anticoagulants.1 We describe a change in the international normalized ratio (INR) that was caused by the consumption of fiddleheads.
W.R. Bartle, Guylaine Ferland
openaire   +1 more source

Prothrombin Time/International Normalized Ratio

2013
Prothrombin time (PT) and/or International Normalized Ratio (INR) is the most commonly used coagulation assay in health care, to diagnose the risk of bleeding and to monitor oral anticoagulation therapy. This test is based on the principle that in citrated plasma, the addition of a thromboplastin and CaCl2 allows for formation of a stable clot.
openaire   +2 more sources

International Normalized Ratio: Towards Improved Accuracy

Thrombosis and Haemostasis, 1999
Oral anticoagulants such as warfarin, acenocoumarin, and phenprocoumon induce depletion of vitamin K-dependent coagulation factors, causing prolongation of the prothrombin time (PT) and the International Normalized Ratio (INR). Commercially available thromboplastin reagents used for the determination of the PT vary in their response to coagulation ...
openaire   +2 more sources

Effects of prednisone on the International Normalized Ratio

American Journal of Health-System Pharmacy, 2006
The effects of prednisone on the International Normalized Ratio (INR) values of a patient were examined.A 66-year-old white man with a history of multiple myeloma was treated in an ambulatory care anticoagulation clinic for deep vein thrombosis. His INR values were normal during therapy with warfarin 14 mg weekly and thalidomide 300 mg daily.
Julie A, Stading   +3 more
openaire   +2 more sources

Effect of Lepirudin on the International Normalized Ratio

Annals of Pharmacotherapy, 2005
BACKGROUND: Many patients receiving direct thrombin inhibitor (DTI) therapy require transition to warfarin. This transition may be complicated by DTI-induced elevations in the international normalized ratio (INR). While the effect of argatroban on the INR has been characterized, data assessing the effect of lepirudin on the INR are limited.
Jennifer L, Stephens   +3 more
openaire   +2 more sources

Monitoring Warfarin Therapy with the International Normalized Ratio

Annals of Pharmacotherapy, 1994
OBJECTIVE: To report a case of suboptimal warfarin monitoring. CASE SUMMARY: A patient with a history of rheumatic heart disease and a mechanical mitral valve was admitted to the local hospital complaining of left-sided weakness. At the time, she was receiving warfarin 5 mg/d. Upon admission her prothrombin time (PT) was 15 s.
openaire   +2 more sources

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