Results 41 to 50 of about 615,889 (293)

Essay on the interaction between external debt and capital outflow from Russia

open access: yesVestnik MGIMO-Universiteta, 2012
The article is devoted to interaction between capital outflow and external debt. We analyze the debt capital market in Russia in 2000s and provide a mechanics of crisis in 2008 – 2009. Based on the theory of R. Caballero and S.
A. V. Ponomarev, V. A. Borisenkov
doaj   +1 more source

A Study on How International Portfolio Investment Flows Affect Macrofinancial Risks and Control Channels

open access: yesDiscrete Dynamics in Nature and Society, 2023
In the current complex global economic background, international capital flows are becoming more frequent. Based on this, this paper takes international portfolio investment as the research object and empirically tests the causal relationship and control
Chaoyi Yu, Zhice Wang
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The role of international reserves on real exchange rate: a panel data analysis

open access: yesEconomia Aplicada, 2022
This article analyzes whether the accumulation of international reserves affects real exchange rates for a set of 57 economies. Panel ARDL estimations, for annual data from 1994 to 2017, show that higher (lower) levels of international reserves cause ...
Flavio Vilela Vieira   +1 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Changes and Analytical Techniques in Volatile Flavor Compounds in Dried Agricultural Products: A Review

open access: yesFoods
Drying is a key step in the primary processing of agricultural products. It alters the type and content of volatile flavor compounds (VOCs), imparting distinctive flavors to the products.
Pengxiao Chen   +7 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Should cryptocurrencies be included in the portfolio of international reserves held by central banks?

open access: yesCogent Economics & Finance, 2016
In most countries, the central bank is required to hold reserve assets as a means of providing credibility for the value of the fiat currency. These assets can be in the form of gold, foreign exchange or some other internationally recognised reserve ...
Winston Moore, Jeremy Stephen
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Oil and Gas in the Arctic: Legal Status and Reserves

open access: yesVestnik MGIMO-Universiteta, 2014
When researching such a hot topic as development of oil and gas reserves in Artie it's crucial to answer 3 key questions. What is legal status of Artie reserves and Russian offshore zone in Arctic?
Nicolay N. Shvets, Polina V. Beresneva
doaj   +5 more sources

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