Results 101 to 110 of about 16,906,885 (293)

Incorporating Climate Spatial Heterogeneity, Rarity, and Temporal Stability to Identify Optimal Climate Refugia

Ecosystem Health and Sustainability
The identification of climate refugia is a crucial conservation strategy under climate change. However, the debate is open on the appropriate climate indicators for refugia delineation.
Jian Zhou, Feiling Yang, Wenbo Yan, Ruidong Wu   +3 more
doaj   +1 more source

Food security : making a difference through research; research that feeds the world [PDF]

, 2013
French version available in IDRC Digital Library: Sécurité alimentaire : faire évoluer les choses au moyen de la recherche; nourrir la population mondiale grâce à la rechercheSpanish version available in IDRC Digital Library: Seguridad alimentaria : la ...
IDRC. Canadian International Food Security Research Fund (CIFSRF)
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Effects of pattern dynamics on carbon storage capacity in the Qinghai-Tibetan Plateau from 1980 to 2020

Scientific Reports
The synergistic effects of landscape composition and spatial configuration are critical for regulating terrestrial carbon storage. However, their dynamic relationships and driving pathways remain poorly understood, especially in high-altitude semi-arid ...
Jiajia Li, Guohua Liu, Xukun Su, Junyan Zhao, Lingli Zuo, Shuyuan Zheng, Kui Luo   +6 more
doaj   +1 more source

Altitudinal pattern of runoff and its change during 1980–2020 in the Yarkant River, Northwest China

Journal of Hydrology: Regional Studies
Study region: The study area is the Upper Yarkant Basin (UYB), located on the northwest edge of Tibetan Plateau. Study focus: Understanding the spatial and temporal dynamics of glacier and snowmelt runoff is key to assessing water resource variability in
Jinyue Wei, Shiyin Liu, Yu Zhu, Xianhe Zhang, Ying Yi, Fuming Xie, Yiyuan Shen, Hanqiang Tian, Chaobing Chen   +8 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

A reconstructed PDO history from an ice core isotope record on the central Tibetan Plateau

npj Climate and Atmospheric Science
Ice core oxygen isotope (δ18O) records from low-latitude regions preserve high-resolution climate records in the past, yet the interpretation of these ice core δ18O records is still facing difficulty due to the uncertainty of ice core dating.
Shijie Li, Lide Tian, Zhongyin Cai, Di Wang, Lili Shao, Xiaoyi Yang, Shangjie Wang, Feng Liu, Pengbin Liang   +8 more
doaj   +1 more source

Application of traditional and reverse labeling approaches to assess dietary bioavailability of metals in biofilms

Environment International
The accuracy of stable isotope tracing techniques, traditional and reverse labeling, in evaluating metal bioavailability remains uncertain. This study employed pulse-chase feeding combined with multi-heavy-metal stable isotope labeling to compare the ...
Yunuo Duan, Shiqi Zhu, Yuxuan Song, Dan Zhu, Mei Zhong, Liqiang Chen, Xia Luo   +6 more
doaj   +1 more source

Emerging Life Sciences and Possible Threats to International Security. [PDF]

Orbis, 2020
Kosal ME.
europepmc   +1 more source