Results 191 to 200 of about 1,144,194 (238)

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

Genitourinary Pathology Society and International Society of Urological Pathology White Paper on Defining Indolent Prostate Cancer. [PDF]

open access: yesAm J Surg Pathol
Shah RB   +28 more
europepmc   +1 more source

Antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). [PDF]

open access: yesVet Dermatol
Loeffler A   +9 more
europepmc   +1 more source

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). [PDF]

open access: yesVet Dermatol
Loeffler A   +9 more
europepmc   +1 more source

Outcomes from the International Society of Nephrology Hemolytic Uremic Syndromes International Forum. [PDF]

open access: yesKidney Int
Kavanagh D   +20 more
europepmc   +1 more source

The Globalization of International Society

2017
This chapter lays the conceptual and theoretical foundations for the volume. It begins by examining four accounts of the globalization of international society. Of these, only Bull and Watson offer a robust account of how the social order of states became global.
Reus-Smit, Christian, Dunne, Tim
openaire   +2 more sources

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