Results 81 to 90 of about 3,532,081 (272)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Measuring New Zealand students' international capabilities: an exploratory study [PDF]

open access: yes
Executive summary: This exploratory study considers the feasibility of measuring New Zealand senior secondary (Years 12/13) students’ \u27international capabilities\u27. Building on background work undertaken by the Ministry’s International Division, the
Liesje Stevens   +2 more
core  

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

University fees: what students pay in deregulated markets [PDF]

open access: yes
Overview For more than a year Australia has debated deregulating university fees for domestic undergraduates. The issue is controversial, but for many years fees have been deregulated for international students and domestic postgraduate coursework ...
Andrew Norton, Ittima Cherastidtham
core  

Intensive English language program for overseas students at Malaysian private tertiary education institutions [PDF]

open access: yes, 2007
As Malaysia is positioning itself to be a regional center of educational excellence, efforts are taken to recruit international students from other countries in the region to pursue international tertiary education, with English as the language of ...
Nurtjahja, Oktavia R.   +1 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Role of Metformin in Preventing New-Onset Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus

open access: yesPharmaceuticals
Background: Recent evidence supports the protective role of metformin on kidney function in patients with type 2 diabetes mellitus. However, its potential to prevent new-onset chronic kidney disease (CKD) in patients with type 2 diabetes mellitus with ...
Yu-Ling Lin   +10 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

ASSESSMENT OF FLEXIBLE PAVEMENT CONDITION USING PCI: A CASE STUDY

open access: yesRevista Eídos
The pavement condition index (PCI) is an inexpensive and simple method to evaluate pavement distresses. The main purpose of this study is to identify and evaluate pavement distress of Jalalabad highway using pavement condition index (PCI) to find a ...
Rohid Dost   +3 more
doaj   +1 more source

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