Results 81 to 90 of about 3,569,842 (293)
Intensive English language program for overseas students at Malaysian private tertiary education institutions [PDF]
, 2007 As Malaysia is positioning itself to be a regional center of educational excellence, efforts are taken to recruit international students from other countries in the region to pursue international tertiary education, with English as the language of ...
Nurtjahja, Oktavia R. +1 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
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International Journal of Medical Students, 2013 International Journal of Medical Students
doaj +6 more sources
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
From English to undergraduate: the international student experience [PDF]
, 2007 Over 3,000 international students study at Northumbria, of whom over 70% originating from the Pacific Rim region choose to study programmes within Newcastle Business School (NBS). On a regular basis, large and small scale learning and teaching experience
Gannon-Leary, Pat, Smailes, Joanne
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Measuring New Zealand students' international capabilities: an exploratory study [PDF]
Executive summary: This exploratory study considers the feasibility of measuring New Zealand senior secondary (Years 12/13) students’ \u27international capabilities\u27. Building on background work undertaken by the Ministry’s International Division, the
Liesje Stevens +2 more
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
PharmaceuticalsBackground: Recent evidence supports the protective role of metformin on kidney function in patients with type 2 diabetes mellitus. However, its potential to prevent new-onset chronic kidney disease (CKD) in patients with type 2 diabetes mellitus with ...
Yu-Ling Lin +10 more
doaj +1 more source