Results 61 to 70 of about 5,011,630 (355)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

SOCIOLECT FORMATION ON THE INTERNET COMMUNICATION

open access: yes, 2018
In this article, the current problem of the formation of the sociolect of informal Internet communication is considered. As a source of work material, messages from users (non-professionals) from various web-forums are taken.

core   +1 more source

A novel middleware for the mobility management over the Internet [PDF]

open access: yes, 2008
The features of mobility, which enormously impact on how communication is evolving into the future, represent a particular challenge in today’s wireless networking research. After an identification and evaluation of the gap between the discontinuities of
Emmanuel Lochin   +7 more
core   +1 more source

Is DNS Ready for Ubiquitous Internet of Things?

open access: yesIEEE Access, 2019
The vision of the Internet of Things (IoT) covers not only the well-regulated processes of specific applications in different areas but also includes ubiquitous connectivity of more generic objects (or things and devices) in the physical world and the ...
Zhiwei Yan   +4 more
doaj   +1 more source

Millimeter-Wave Communication for Internet of Vehicles: Status, Challenges, and Perspectives

open access: yesIEEE Internet of Things Journal, 2020
The Internet of Vehicles has attracted a lot of attention in the automotive industry and academia recently. We are witnessing rapid advances in vehicular technologies that comprise many components, such as onboard units (OBUs) and sensors.
Kayhan Zrar Ghafoor   +7 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The Internet for the medical and scientific community [PDF]

open access: yesMolecular Human Reproduction, 1998
With the explosion of data coming out from the international scientific community, researchers can now locate and manipulate data of interest quickly and easily on the Internet. The scope of this review is to focus on some of the recent developments of the Internet that are specially relevant to health scientists.
M C, Simmler, P, Dessen
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Enhancing microbial fuel cell performance with carbon powder electrode modifications for low-power sensors modules

open access: yesInternational Journal of Renewable Energy Development
Microbial Fuel Cell (MFC) is a promising technology for harnessing energy from organic compounds. However, the low power generation of MFCs remains a significant challenge that hinders their commercial viability. In this study, we reported three distinct
Mohammed Adel Al-badani   +2 more
doaj   +1 more source

High-Resolution Representations Network for Single Image Dehazing

open access: yesSensors, 2022
Deep learning-based image dehazing methods have made great progress, but there are still many problems such as inaccurate model parameter estimation and preserving spatial information in the U-Net-based architecture. To address these problems, we propose
Wensheng Han   +4 more
doaj   +1 more source

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