Results 91 to 100 of about 1,813,668 (335)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Internet Memes in Network Communication: English Entertainment Sites

Виртуальная коммуникация и социальные сети, 2022
Internet memes are an integral part of the Internet entertainment discourse. They are often based on precedent phenomena and reflect current events, facilitate the self-expression of the author, create a comic effect, etc.
Svetlana Yu. Dashkova
doaj  

Interpretation of a verbal-visual communication [PDF]

, 2017
In contemporary internet-dominated everyday life, ever more often one faces communications which utilise both verbal (words) and iconic (images) codes. In the article, I analyse two types of said communications: advertisements and memes. Both advertising
Habrajska, Grazyna
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Decoding the Metaphor of Internet Meme: A Study of Satirical Tweets on Black Friday Sales in Nigeria

, 2017
This study examined an emerging trend in Internet discourse as metaphorical constructs used by individuals for communication online. The Internet meme is an evolving trend used for satirical illustrations and expression of intents in multimodal ways ...
S. Anurudu, Isioma Maureen Obi
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

INTERNET MEMES WITH ENGLISH IDIOMS

Вестник Тверского государственного университета. Серия: Филология, 2022
Статья предлагает структурно-семантический анализ интернет-мемов с английскими фразеологическими единицами. Интернет-мем понимается в данной статье как креолизованный текст, содержащий вербальные и невербальные компоненты. В результате дефразеологизации фразеологической единицы с последующим ее реструктурированием в рамках данных поликодовых единств ...
openaire   +1 more source

Notes on the Margins of Metadata; Concerning the Undecidability of the Digital Image [PDF]

, 2013
This paper considers the significance of metadata in relation to the image economy of the web. Social practices such as keywording, tagging, rating and viewing increasingly influence the modes of navigation and hence the utility of images in online ...
Rubinstein, Daniel, Sluis, Katrina
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source