Results 41 to 50 of about 173,706,990 (295)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Privacy Management in Social Internet of Vehicles: Review, Challenges and Blockchain Based Solutions

IEEE Access, 2019
The Internet of Things (IoT) paradigm has integrated the sensor network silos to the Internet and enabled the provision of value-added services across these networks.
Talal Ashraf Butt, Razi Iqbal, Khaled Salah, Moayad Aloqaily, Yaser Jararweh   +4 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

A Privacy-Preserving and Fault-Tolerant Data Aggregation Scheme with User-Driven Differentiated Access for V2G Interaction Service

World Electric Vehicle Journal
Vehicle-to-Grid (V2G) enables energy and information exchange between electric vehicles (EVs) and the power grid. Large amounts of distributed data are generated in V2G systems. The charging data of EVs connected to charging piles (CPs) are aggregated by
Nan Zhang, Fan Yang, Quangui Hu, Peijun Li, Wenkui She, Jian Xu, Tianbao Liu, Nian Wang   +7 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Intelligent augmented keyword search on spatial entities in real-life internet of vehicles

, 2018
Internet of Vehicles (IoV) has attracted wide attention from both academia and industry. Due to the popularity of the geographical devices deployed on the vehicles, a tremendous amount of spatial entities which include spatial information, unstructured ...
Tian, Shasha, Anjum, Ashiq, Du, Xiaokun, Zhu, Rongbo, Li, Yanhong, Wang, Meng, Luo, Changyin, Feng, Yuhe   +7 more
core   +1 more source

Feature extraction and dynamic identification of driving intention adapting to multi-mode emotions

Advances in Mechanical Engineering, 2019
Accurate identification of driving intention and reasonable control of driver’s behavior is seen as an important mean to reduce man-made traffic accidents for the intelligent vehicle.
Xiao-yuan Wang, Ya-qi Liu, Qing Xu, Yuan-yuan Xia, Hai-xia Zhao, Shi-jie Liu, Jun-yan Han   +6 more
doaj   +1 more source

Optimal Scheduling Strategy for Micro Energy Internet Under Electric Vehicles Aggregation

Zhongguo dianli, 2023
With the continuous access of renewable energy to the power grid, more energy storage equipment is required to reduce the peak-to-valley difference, which greatly increases the power generation cost.
Jiakun AN, Shuqiang YANG, Tao WANG, Chunguang HE, Jing ZHANG, Chao YUAN, Chunxia DOU   +6 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Information Service System for Internet of Vehicles [PDF]

, 2019
This system is an Android mobile phone information service system for internet of vehicles. The information service system has four types of functions, including a login registration function, an information search function, a location function, and an ...
Xing Xue, Xue Xing, Chenyang Liu, Liu Chenyang   +3 more
core   +2 more sources