Results 221 to 230 of about 593,997 (297)

High‐Dose Pulse Glucocorticoid Treatment Prevents White Matter Spinal Cord Pseudoatrophy in Newly Diagnosed Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Spinal cord (SC) atrophy correlates with and predicts the underlying progressive biology in active and non‐active multiple sclerosis (MS), thereby providing a biomarker for clinical trials and patient management. Initiation of disease‐modifying therapy (DMT) may be followed by early pronounced central nervous system (CNS) volume loss due to ...
Simone Sacco   +26 more
wiley   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam   +29 more
wiley   +1 more source

Gold Nanoclusters as Smart Nanoplatforms for Targeted Cancer Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
A folic acid‐targeted gold nanocluster platform is developed for tumor‐specific delivery and radiofrequency (RF)‐triggered release of doxorubicin. Enhanced uptake, nuclear localization, and therapeutic efficacy are confirmed in 2D and 3D spheroid models.
Samad Mussa Farkhani   +6 more
wiley   +1 more source

Electron Spin Resonance at the Single‐Molecule Scale

open access: yesAngewandte Chemie International Edition, EarlyView.
This minireview provides an overview of the four electron‐spin‐resonance techniques with single‐molecule sensitivity, relying on either optically detected magnetic resonance or scanning‐probe microscopy. After introducing underlying common concepts, it reviews the working principles, experimental conditions and key achievements.
Lisanne Sellies, Jascha Repp
wiley   +1 more source

Characterization of Lightweight Polymeric Honeycomb Structures for Use as Backsides in Glass‐Free PV Modules

open access: yesJournal of Applied Polymer Science, EarlyView.
This study evaluates PET‐ and PP‐based honeycomb sandwich composites with glass fiber‐reinforced skins as lightweight backsheets for photovoltaic modules. Mechanical, optical, and thermal properties are assessed. Glass fiber embedment quality influences strength and moisture resistance.
Nikolina Pervan   +8 more
wiley   +1 more source

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