Results 151 to 160 of about 22,700 (236)

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Interoception and dissociation in migraine: a case–control study of chronic and episodic subtypes

Frontiers in Neurology
BackgroundMigraine is one of the most common neurological disorders. Despite advances in understanding of episodic migraine, little is understood about the mechanisms underlying the chronification of migraine.
Akihiro Koreki, Akihiro Koreki, Vilomi Bhatia, Anne-Marie Logan, Usman Khan, Mitsumoto Onaya, Sarah Garfinkel, Hugo Critchley, Mark Edwards, Niranjanan Nirmalananthan, Mahinda Yogarajah, Mahinda Yogarajah   +11 more
doaj   +1 more source

Functional Connectivity During Social Reward Processing in Autistic and Neurotypical Adolescents

Brain and Behavior, Volume 16, Issue 5, May 2026.
Heightened task‐evoked functional connectivity was observed in autistic youth between the amygdala and the posterior superior temporal sulcus (pSTS), core regions of the social reward circuitry, on receipt of a social‐interactive reward. The strength of connectivity was negatively correlated with enjoyment of social interaction.
Hua Xie, Dustin Moraczewski, Kathryn A. McNaughton, Katherine R. Warnell, Junaid S. Merchant, Laura A. Kirby, Elizabeth Redcay   +6 more
wiley   +1 more source

Regional Brain Activity Alterations in Social Anxiety Disorder Revealed by Seed‐Based d Mapping With Permutation of Subject Images

Brain and Behavior, Volume 16, Issue 5, May 2026.
This SDM‐PSI meta‐analysis identified consistent regional brain activity alterations in social anxiety disorder, including hyperactivity in the left superior parietal gyrus, right cerebellum, and right supramarginal gyrus, and hypoactivity in the left insula and right supplementary motor area, with age and symptom severity modulating specific regions ...
Sen Li, Ziqi Zhang, Shanling Ji, Aoxue Zhang, Shengbo Han, Zhengyang Chang, Kun Li, Jian Cui, Hao Yu, Chuanxin Liu, Cong Zhou   +10 more
wiley   +1 more source

The role of interoceptive awareness in social anxiety disorder – results of an internet-based CBT-manualized therapist delivered group-treatment

BMC Psychology
Background Interoception, the process of detecting internal bodily signals, is linked to emotional regulation and mental health. Dysregulated interoceptive awareness (IAw) is associated with psychopathology, including social anxiety disorder (SAD), where
I. Schmalbach, K. Petrowski
doaj   +1 more source

Interoceptive sensibility: links with insomnia symptoms, anxiety, and depression in the general population

Comprehensive Psychiatry
Background: Diurnal and nocturnal symptoms of insomnia are strongly associated with anxiety and depression. Interoception provides a new reading window for understanding the development and maintenance of psychopathology and sleep disorders.
Faccini Julie, Joshi Vrutti, Del-Monte Jonathan   +2 more
doaj   +1 more source

The Impact of BWM‐T Versus Brief Mindfulness Induction on Stress, Anxiety and Self‐Efficacy in University Students: Immediate and Short‐Term Outcomes of RCT on Psychological Well‐Being and Autonomic Balance

Brain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Background: University students face increasing levels of stress, anxiety, and self‐efficacy, which may disrupt autonomic balance. While many mind–body interventions require sustained practice, growing evidence suggests that even a single session can yield immediate benefits.
Mauro Cozzolino, Marco Borgese, Giovanna Celia   +2 more
wiley   +1 more source

The Effectiveness of Psychological Treatment for Anorexia Nervosa in Adolescents: A Critical Review of Randomized Controlled Trials

International Journal of Eating Disorders, Volume 59, Issue 5, Page 829-853, May 2026.
ABSTRACT Objective Although international treatment guidelines for eating disorders recommend varying psychological approaches for adolescents with anorexia nervosa (AN), most existing reviews have combined adolescent and adult samples, leaving the overall evidence base for this population poorly defined.
Renée A. Broersma, Moniek A. J. Zeegers, Jesse Roest, Ramon J. L. Lindauer, Fabienne Harteveld, Peer van der Helm, James Lock, Mark Assink   +7 more
wiley   +1 more source

Clinical Outcomes After Temperament Based Therapy With Support (TBT‐S): A 12‐Month Naturalistic Follow‐Up Study

European Eating Disorders Review, Volume 34, Issue 3, Page 722-731, May 2026.
ABSTRACT Objective This study investigated clinical outcomes in a mixed sample of adult patients with an eating disorder (ED) after receiving Temperament Based Therapy with Support (TBT‐S) at a tertiary eating disorder clinic. Method A naturalistic 12‐month follow‐up study of 46 patients and 65 supports who received the 5‐day TBT‐S treatment was ...
Joakim Skoog, Ingrid Funderud, Kristin Stedal   +2 more
wiley   +1 more source

GLP‐1 Receptor Agonists for Treating Alcohol Use Disorder: A Critical Review

Alcohol, Clinical and Experimental Research, Volume 50, Issue 5, May 2026.
This narrative review of the development of GLP‐1 receptor agonists provides a foundation for both preclinical and clinical research on their use for treating alcohol use disorder (AUD). Both observational studies using real‐world data and randomized controlled clinical trials support the potential utility of these medications for treating AUD ...
Sean Woo, Grace Zhu, Chrismely Castro, Allen Phuong, Aadita Roy, Christal N. Davis, Henry R. Kranzler   +6 more
wiley   +1 more source