Results 141 to 150 of about 248,441 (319)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Fuzzy rule interpolation for multidimensional input spaces in determining d50c of hydrocyclones

open access: yes, 2003
Fuzzy rule-based systems have been very popular in many engineering applications. In mineral engineering, fuzzy rules are normally constructed using some fuzzy rule extraction techniques to establish the determination model in predicting the d50c of ...
Wong, K.W.   +3 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

A Recursive Non-Uniform Sampling Estimator for Asynchronous Nonlinear Systems

open access: yesSensors
In this paper, we consider the problem of asynchronous estimation in the presence of packet losses for the randomly sampling nonlinear system. Packet losses occur at the control input and at the measurement side.
Yu-Hang Yang   +2 more
doaj   +1 more source

A behavioral view of Nevanlinna-Pick interpolation

open access: yes, 2005
The classical Nevanlinna-Pick (NP) interpolation problem is about finding a rational function that satisfies given interpolation conditions, along with a norm condition.
PILLAI, HARISH K   +3 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Fast Refrigerant Property Calculations Using Interpolation-Based Methods

open access: yes, 2012
An interpolation-based method for computing refrigerant properties which can be used in simulations of vaporcompression air-conditioning equipment is presented.
Laughman, Christopher   +2 more
core  

Usage of spline interpolation in catheter-based cardiac mapping

open access: yes, 2010
Due to their minimal invasiveness catheters are highly preferred in cardiac mapping techniques used in the source localization of rhythm disturbances in the heart.
Yilmaz, Bulent   +2 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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