Results 131 to 140 of about 248,441 (319)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Evaluation by simulation of interpolation and acceleration algorithms for Stepper Motors
, 2005 Stepper motors are used to control CNC machines for many applications. As well as following the required path precisely, it is also important that the motion be smooth and that the surface speed be controllable.
Chow, YK +4 more
core
, 2020 Differentiable non-uniform interpolation: https://arxiv.org/abs/2012 ...
Skorokhodov, Ivan
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Fuzzy rule interpolation for multidimensional input space with petroleum engineering application
, 2001 Fuzzy rule based systems have been very popular in many engineering applications. In petroleum engineering, fuzzy rules are normally constructed using some fuzzy rule extraction techniques to establish the petrophysical property prediction model. However,
Wong, K.W., Gedeon, T.D.
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Monatshefte für Mathematik, 1984 Triangular interpolation problems (problems with biorthogonal polynomial sequence) are studied. Convergence of the corresponding interpolation series in investigated. It is shown that the interpolation polynomials form a basis in appropriate nuclear Fréchet spaces.
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source