Results 111 to 120 of about 248,441 (319)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Interpolation of Instantaneous Air Temperature Using Geographical and MODIS Derived Variables with Machine Learning Techniques

ISPRS International Journal of Geo-Information, 2019
Several methods have been tried to estimate air temperature using satellite imagery. In this paper, the results of two machine learning algorithms, Support Vector Machines and Random Forest, are compared with Multiple Linear Regression and Ordinary ...
Marcos Ruiz-Álvarez, Francisco Alonso-Sarria, Francisco Gomariz-Castillo   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

On Hermite Interpolation

Journal of Approximation Theory, 2000
The author gives estimations of bounds for the fundamental functions of Hermite interpolation of higher order on an arbitrary system of nodes. Those estimations are applied for investigations of convergence of Hermite interpolation and Hermite-Fejér-type interpolation of higher order.
openaire   +2 more sources

Error bound for radial basis interpolation in terms of a growth function

, 2007
We suggest an improvement of Wu-Schaback local error bound for radial basis interpolation by using a polynomial growth function. The new bound is valid without any assumptions about the density of the interpolation centers.
Davydov, Oleg
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Interpolation of Martingales

The Annals of Probability, 1977
We show that every discrete-time martingale can be interpolated to give a continuous, continuous-time martingale, and provide a necessary and sufficient condition for the existence of an interpolated martingale with no flat spots.
openaire   +3 more sources

Space-Time Transfinite Interpolation of Volumetric Material Properties

, 2014
The paper presents a novel technique based on extension of a general mathematical method of transfinite interpolation to solve an actual problem in the context of a heterogeneous volume modelling area.
Fryazinov, Oleg, Adzhiev, Valery, Pasko, Alexander, Comninos, Peter, Sanchez, Mathieu   +4 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Rewriting Interpolants

Electronic Notes in Theoretical Computer Science, 2008
AbstractWe give a method of constructing an interpolant for linear equality, and inequality constraints over the rational numbers. Our method is based on efficient rewriting techniques, and does not require the use of combination methods. The interpolant is constructed in such a way that it reflects the structure of the rewrite proof.
Christopher Lynch, Yuefeng Tang
openaire   +1 more source