Results 31 to 40 of about 635,053 (187)
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Macro-element interpolation on tensor product meshes [PDF]
A general theory for obtaining anisotropic interpolation error estimates for macro-element interpolation is developed revealing general construction principles.
Schopf, Martin
core
Let \mathbb K denote an algebraically closed field. We study the relation between an ideal I\subseteq\mathbb K[x_1,\ldots,x_n] and its cross sections I_\alpha=I+\langle x_1-\alpha\rangle
Martín Avendaño, Jorge Ortigas Galindo
openaire +4 more sources
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring+6 more
wiley +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek+15 more
wiley +1 more source
A Discrete Adapted Hierarchical Basis Solver For Radial Basis Function Interpolation
In this paper we develop a discrete Hierarchical Basis (HB) to efficiently solve the Radial Basis Function (RBF) interpolation problem with variable polynomial order.
Castrillon-Candas, Julio Enrique+2 more
core +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Kernel Interpolation for Scalable Structured Gaussian Processes (KISS-GP) [PDF]
We introduce a new structured kernel interpolation (SKI) framework, which generalises and unifies inducing point methods for scalable Gaussian processes (GPs).
Nickisch, Hannes, Wilson, Andrew Gordon
core +2 more sources
Some remarks on non-symmetric interpolation Macdonald polynomials
We provide elementary identities relating the three known types of non-symmetric interpolation Macdonald polynomials. In addition we derive a duality for non-symmetric interpolation Macdonald polynomials.
Sahi, Siddhartha, Stokman, Jasper
core +1 more source