Results 41 to 50 of about 119,617,328 (270)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Fast Linear Canonical Transform for Nonequispaced Data
Fractal and Fractional, 2023 The investigations of the discrete and fast linear canonical transform (LCT) are becoming one of the hottest research topics in modern signal processing and optics.
Yannan Sun, Wenchao Qian
doaj +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
IET Control Theory & Applications, 2021 Here, agents learn how often to exchange information with neighbours in cooperative multi‐agent systems (MASs) such that their linear quadratic regulator (LQR)‐like performance indices are minimized. The investigated LQR‐like cost functions capture trade‐
Ivana Palunko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
IET Control Theory & Applications, 2021 A polynomial filtering algorithm is designed for estimating a Markov sequence based on linear measurements. The feature of the estimation problem is that the Markov sequence is described by a nonlinear shaping filter, which is a second‐order polynomial ...
O. A. Stepanov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Modified Fourier expansions: theory, construction and applications [PDF]
, 2010 Modified Fourier expansions present an alternative to more standard algorithms for the approximation of nonperiodic functions in bounded domains. This thesis addresses the theory of such expansions, their effective construction and computation, and ...
core +2 more sources
APPLICATION OF B-SPLINE METHOD IN SURFACE FITTING PROBLEM [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019 Fitting a smooth surface on irregular data is a problem in many applications of data analysis. Spline polynomials in different orders have been used for interpolation and approximation in one or two-dimensional space in many researches. These polynomials
F. Esmaeili +3 more
doaj +1 more source