Results 161 to 170 of about 424,704 (329)

Uncertainty Quantification for Interpretable Constitutive Models using Genetic Programming based Symbolic Regression

, 2023
Karl Garbrecht, John M Emery, Coleman Alleman, Brian Lester, Geoffrey Bomarito, Michael Buche, Jacob Hochhalter   +6 more
openalex   +1 more source

Interpreting Interpretative Errors

Zbornik radova Pravnog fakulteta u Splitu
This article examines the attribution of interpretative errors in judicial decision-making, a recurring yet under-theorised element of legal practice. It highlights how ideologies of legal interpretation and legal decision-making shape the criteria for evaluating interpretative correctness and critiques traditional dichotomies between axiological and ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Application of artificial intelligence in schizophrenia rehabilitation management: a systematic scoping review. [PDF]

Transl Psychiatry
Yang H, Chang F, Muroi F, Liu Z, Zhang W, Cai J.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Comment on "Overnight Dexamethasone in Primary Aldosteronism Screening in Patients on Interfering Therapy (ODEPRASC): A Diagnostic Interpretability Study Protocol". [PDF]

J Clin Hypertens (Greenwich)
Sarkar R, Borah S, Dharani N.
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

From Disease-Specific Models to Broad Clinical Utility: A Perspective on AI Hybrid Ensemble Frameworks. [PDF]

Adv Genet (Hoboken)
Zhang H, Zhang G, Yu C, Wu R, Zhang S, Huang X, Yuan Y, Chen Y, Pei S, Zhang G.   +9 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A reinforcement learning-guided interpretable method for postoperative sepsis prediction with Hilbert-Schmidt Independence Criterion. [PDF]

Front Big Data
Zhong K, Chen H, Sun Q, Wang P, Liu Z, Chen Y.   +5 more
europepmc   +1 more source