Results 161 to 170 of about 244,685 (311)

scE²TM improves single-cell embedding interpretability and reveals cellular perturbation signatures. [PDF]

Nat Commun
Chen H, Lu Y, Zhao Y, Dai Z, Wang FL, Li Q, Rao Y, Li Y.   +7 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Developing an Interpretable Machine Learning Model for Early Prediction of Cardiovascular Involvement in Systemic Lupus Erythematosus

Journal of Inflammation Research
Zixian Deng,1 Huadong Liu,1 Feng Chen,2 Qiyun Liu,1 Xiaoyu Wang,3 Caiping Wang,1 Chuangye Lyu,1 Jianghua Li,1 Tangzhiming Li1,4 1Department of Cardiology, Shenzhen People’s Hospital (The First Affiliated Hospital, Southern University of Science and ...
Deng Z, Liu H, Chen F, Liu Q, Wang X, Wang C, Lyu C, Li J, Li T   +8 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Beyond surgical showcase: workflow continuity and exploratory AI-oriented video interpretability of robotic low anterior resection videos on YouTube. [PDF]

Front Surg
Ozcan A, Gunes G.
europepmc   +1 more source

The formalization of Interpretability

, 1991
This paper contains a careful derivation of principles of Interpretability Logic valid in extensions of IΔ0 ...
Visser, Albert, Emeriti F&R
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Bridging the black box: artificial intelligence in acute care needs greater interpretability and precision. [PDF]

BMJ Health Care Inform
Wang YC.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Prediction of Postoperative Vomiting Within 24 Hours Using Machine Learning With Large Language Model-Enhanced Interpretability: Development and Validation Study. [PDF]

JMIR Med Inform
Wang HJ, Lee WP, Gau TP, Cheng KI, Wei CR.   +4 more
europepmc   +1 more source