Results 221 to 230 of about 1,818,152 (349)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Response to "Enhancing the XGBoost Mortality Prediction Model for ICU Patients with Acute Ischemic Stroke". [PDF]

Health Data Sci
Cummins JA, Gerber BS, Fukunaga MI, Henninger N, Kiefe CI, Liu F.   +5 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Beyond peak accuracy: a stability-centric framework for reliable multimodal student engagement assessment. [PDF]

Sci Rep
Almuniri IS, Alhussian H, Aziz N, Khairy SOF, AlAbri AS, Jarallah ZF, Yahaya S, Adamu S.   +7 more
europepmc   +1 more source

Exploring altered body perception and comfort after stroke: An interpretive phenomenological analysis [PDF]

, 2018
Hannah Stott, Mary Cramp, Stuart McClean, Ailie Turton   +3 more
openalex  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Dual-Path Convolutional Neural Network with Squeeze-and-Excitation Attention for Lung and Colon Histopathology Classification. [PDF]

J Imaging
AlShehri H.
europepmc   +1 more source

Simple means to improve the interpretability of regression coefficients

, 2010
H. Schielzeth
semanticscholar   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Explainable Cluster-Based Predictive Framework for Early Diagnosis of Autism Spectrum Disorder Using Behavioral Biomarkers. [PDF]

Diagnostics (Basel)
Alshammeri M, Ahmad Z, Humayun M, Alamri M.   +3 more
europepmc   +1 more source