Results 41 to 50 of about 295,552 (260)

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

Geometric Reasoning in the Embedding Space

Machine Learning and Knowledge Extraction
While neural networks can solve complex geometric problems, as demonstrated by systems like AlphaGeometry, we have limited understanding of how they internally represent and reason about spatial relationships.
David Mojžíšek, Jan Hůla, Jiří Janeček, David Herel, Mikoláš Janota   +4 more
doaj   +1 more source

Inverse Classification for Comparison-based Interpretability in Machine Learning

, 2017
In the context of post-hoc interpretability, this paper addresses the task of explaining the prediction of a classifier, considering the case where no information is available, neither on the classifier itself, nor on the processed data (neither the ...
A Watson, D Baehrens, D Martens, E Štrumbelj, JD Tygar, JM Alonso, K Fernandes, LA Hendricks, M Gacto, MV Mannino, N Mvududu, R Harman, T Gog van, Y LeCun   +13 more
core   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

A Review of Explainable Artificial Intelligence from the Perspectives of Challenges and Opportunities

Algorithms
The widespread adoption of Artificial Intelligence (AI) in critical domains, such as healthcare, finance, law, and autonomous systems, has brought unprecedented societal benefits.
Sami Kabir, Mohammad Shahadat Hossain, Karl Andersson   +2 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Fuzzy-DogNet: A Lightweight and Interpretable Deep Unstructured Neuro-Fuzzy System Based on Band-Pass Filters for Traffic Sign Recognition

IEEE Access
Traffic Sign Recognition (TSR) plays a critical role in autonomous driving and advanced driver-assistance systems, necessitating accurate and efficient recognition under real-world constraints.
Sadra Berangi, Mohammad Mahdi Parchamijalal, Armin Salimi-Badr   +2 more
doaj   +1 more source

Prediction of red blood cell transfusion after orthopedic surgery using an interpretable machine learning framework

Frontiers in Surgery, 2023
ObjectivePostoperative red blood cell (RBC) transfusion is widely used during the perioperative period but is often associated with a high risk of infection and complications.
Yifeng Chen, Xiaoyu Cai, Zicheng Cao, Jie Lin, Wenyu Huang, Yuan Zhuang, Lehan Xiao, Xiaozhen Guan, Ying Wang, Xingqiu Xia, Feng Jiao, Xiangjun Du, Guozhi Jiang, Guozhi Jiang, Deqing Wang   +14 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Signal Processing in the Retina: Interpretable Graph Classifier to Predict Ganglion Cell Responses

IEEE Open Journal of Signal Processing
It is a popular hypothesis in neuroscience that ganglion cells in the retina are activated by selectively detecting visual features in an observed scene.
Yasaman Parhizkar, Gene Cheung, Andrew W. Eckford   +2 more
doaj   +1 more source