Results 111 to 120 of about 244,877 (310)

Mind the Gap: A Generative Approach to Interpretable Feature Selection and Extraction [PDF]

, 2015
We present the Mind the Gap Model (MGM), an approach for interpretable feature extraction and selection. By placing interpretability criteria directly into the model, we allow for the model to both optimize parameters related to interpretability and to ...
Kim, Been, Doshi-Valez, Finale, Shah, Julie A   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Axiomatising tree-interpretable structures

, 2002
We introduce the class of tree-interpretable structures which generalises the notion of a prefix-recognisable graph to arbitrary relational structures.
Achim Blumensath, Rwth Aachen
core   +1 more source

Quantum engineering of qudits with interpretable machine learning

Higher-dimensional quantum systems (qudits) offer advantages in information encoding, error resilience, and compact gate implementations, and naturally arise in platforms such as superconducting and solid-state systems. However, realistic conditions such
Paz-Silva, GA, Youssry, A, Sareen, R, Peruzzo, A, Mayevsky, Y   +4 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A decomposable and interpretable cellular network traffic prediction model based on graph convolutional neural network

Dianxin kexue
With the rapid proliferation of intelligent connected applications in urban environments, the dramatic increase in urban network traffic presents significant challenges.
ZHANG Zitian, WEN Zhixin, ZHUGE Bin, LYU Zhihao, DONG Ligang, JIANG Xian   +5 more
doaj  

Using the excitation/inhibition ratio to optimize the classification of autism and schizophrenia

Translational Psychiatry
The excitation/inhibition (E/I) ratio has been shown to be imbalanced in individuals diagnosed with autism (AT) or schizophrenia (SZ), relative to neurotypically developed controls (TD).
Lavinia Carmen Uscătescu, Christopher J. Hyatt, Jack Dunn, Martin Kronbichler, Vince Calhoun, Silvia Corbera, Kevin Pelphrey, Brian Pittman, Godfrey Pearlson, Michal Assaf   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source