Results 61 to 70 of about 4,361,243 (284)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Mechanisms of overburden deformation associated with the emplacemenet of the Tulipan Sill, Mid-Norwegian Margin [PDF]

open access: yes, 2016
Accounting for i gneous intrusion s in to sedimentary basins is important to the petroleum industry because magmatism deforms the host rock and affects the thermal evolution of a basin, thereby influencing hydrocarbon generation, migration, and ...
Craig Magee   +26 more
core   +1 more source

Current status of science learning in Shanghai and a possible PBL mechanism

open access: yesDiscover Education
China’s 2022 curriculum standards issued by the Ministry of Education prioritize a “competency-oriented” education that highlights the role of science education in improving students’ scientific literacy and competency.
Haiqin Sun, Zhiyuan Gu
doaj   +1 more source

Devising Parameters based on Blended Model of Translation Assessment

open access: yesالإيضاح
Evaluation of translation is a real time challenge in the current emerging trends of translation, neologism and semantic vastness in more than seven thousand languages. The quality in various translation types is the only key to success. Therefore, it is
Shair Ali Khan, Nargis Nazir
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Cenozoic tectonic subsidence in the Upper Assam Basin, NE India

open access: yesGeosystems and Geoenvironment
The Upper Assam Basin is an intermontane foreland basin surrounded by gigantic mountain belts in NE India. The structural geometry of the basin is controlled by the tectonic interactions of the Himalayan orogenic belt in the north, Mishmi thrusts in the ...
Priyadarshi Chinmoy Kumar   +2 more
doaj   +1 more source

Interpretable but not interpreted

open access: yesProceedings of the Amsterdam Colloquium, 2007
This paper takes the position that the interpretive procedure may selectively ignore pieces of an LF that on other occasions it associates with an interpretation. I cite arguments (from earlier work) that pronouns in particular can go uninterpreted.
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Reference-Free Lens-Flare-Aware Detector for Autonomous Driving

open access: yesSensors
As autonomous driving technology advances, the deployment of autonomous vehicles in urban environments is rapidly increasing. Lens flare—an often overlooked optical artifact in object detection research—can lead to increased false positives or missed ...
Shanxing Ma   +6 more
doaj   +1 more source

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