Results 61 to 70 of about 3,708,057 (315)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A modal-Hamiltonian interpretation of quantum mechanics [PDF]

open access: yes, 2008
The aim of this paper is to introduce a new member of the family of the modal interpretations of quantum mechanics. In this modal-Hamiltonian interpretation, the Hamiltonian of the quantum system plays a decisive role in the property-ascription rule that
Castagnino, Mario   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Current status of science learning in Shanghai and a possible PBL mechanism

open access: yesDiscover Education
China’s 2022 curriculum standards issued by the Ministry of Education prioritize a “competency-oriented” education that highlights the role of science education in improving students’ scientific literacy and competency.
Haiqin Sun, Zhiyuan Gu
doaj   +1 more source

Devising Parameters based on Blended Model of Translation Assessment

open access: yesالإيضاح
Evaluation of translation is a real time challenge in the current emerging trends of translation, neologism and semantic vastness in more than seven thousand languages. The quality in various translation types is the only key to success. Therefore, it is
Shair Ali Khan, Nargis Nazir
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Reference-Free Lens-Flare-Aware Detector for Autonomous Driving

open access: yesSensors
As autonomous driving technology advances, the deployment of autonomous vehicles in urban environments is rapidly increasing. Lens flare—an often overlooked optical artifact in object detection research—can lead to increased false positives or missed ...
Shanxing Ma   +6 more
doaj   +1 more source

A guide to Pacific landforms and vegetation for use in photographic interpretation

open access: yes, 1945
1 volume : chiefly illustrations ; 27 x 36 cm. Cover title: Pacific landforms and vegetation. On cover: Air Intelligence Group, Division of Naval Intelligence, Office of the Chief of Naval Operations, Navy Department. "May 1945"--Cover. "OPNAV-16-VP107"--
United States. Naval Photograhic Interpretation Center.
core  

Interpretation of Lyrics, Expression of Song and Subjectivity

open access: yes, 2022
This paper aims to elucidate that interpretating of Lyrics of directly connects how music expression is expressed and moves the conscious of the subject.  The lyrics of teaching materials seem easy to understand. However, being interpretated those deeply,
小池, 順子   +2 more
core  

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