Results 71 to 80 of about 3,708,057 (315)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Cenozoic tectonic subsidence in the Upper Assam Basin, NE India

open access: yesGeosystems and Geoenvironment
The Upper Assam Basin is an intermontane foreland basin surrounded by gigantic mountain belts in NE India. The structural geometry of the basin is controlled by the tectonic interactions of the Himalayan orogenic belt in the north, Mishmi thrusts in the ...
Priyadarshi Chinmoy Kumar   +2 more
doaj   +1 more source

An action research appraisal of visitor center interpretation and change [PDF]

open access: yes, 2007
This study uses an action research framework to evaluate changes to the visitor center-based interpretation of a natural environment. The context for the study is Australia’s Flinders Chase National Park, located in an isolated tourism region, namely ...
Moscardo, Gianna, Pearce, Philip L.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Metacognitive strategies in translation: a comparative study of student and professional translators

open access: yesHumanities & Social Sciences Communications
Translation expertise significantly influences how translators manage cognitive resources, yet the specific ways in which professional and novice translators differ in their metacognitive strategy use remain incompletely understood.
Dahui Dong, Meng-Lin Chen
doaj   +1 more source

On Targets

open access: yesFootprint, 2021
Impact range targets in military training areas can be square, triangular, rectangular, circular, and linear. Some are designed to look like other things, like airbases, villages, convoys, industrial areas, surface-to-air missile sites, and are built out
The Center for Land Use Interpretation CLUI
doaj  

Corporate sustainability from a management accounting perspective and Egyptian reality [PDF]

open access: yesالمجلة العلمية للدراسات والبحوث المالية والتجارية
The article explores the critical relationship between corporate sustainability and management accounting practices, emphasizing that businesses must operate within environmental and social frameworks to achieve long-term financial success.
Wahied Ahmed Abou El Fetouh
doaj   +1 more source

La diglossie littéraire dans les œuvres littéraires nigérianes en traduction française [PDF]

open access: yesAkofena, 2022
Résumé : Il n’est plus à redire que la prose africaine tire ses racines des cultures locales et par défaut le contenu de cette littérature existait tout d’abord en langue indigène avant d’être transposé dans une langue européenne.
Rasheed OYELESO
doaj  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Natural interpretation: a brief guide to the interpretation of nature and wildlife

open access: yes, 2017
Best Practice Guidelines no 13 published on the website of the Association for Heritage ...
Mitchell, Jim, Ryland, Philip
core  

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