Results 41 to 50 of about 601,707 (261)
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Literary Text in Time and Space
Review of the book: Lunkova L.N. Worlds and Spaces of a Literary Text. Moscow, 2020. 160 p. This review gives a high assessment of the monograph written by Larisa N. Lunkova, Doctor of Philology, Professor of Kolomna Theological Seminary.
Tatiana N. Fedulenkova
doaj +1 more source
Associative Experiment as a Method of Interpretation of Discourse
Discursive space is represented as a fragment of linguistic picture of the world, in which there is an emerging conceptual image, fully manifested in the linguistic consciousness.
G.J. Bogdanovich
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Covariant dynamics on the momentum space
A geometrical interpretation of Schrödinger's kinetic and potential energy operators is proposed, allowing for a covariant momentum space formulation of the dynamics that is relevant for the theories with the deformation of the momentum space structure ...
Boris Ivetić
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Experiences With Shared Reading for Promoting Reading Engagement in a Swedish Upper-Secondary School
This article considers students’ and teachers’ perceptions of shared reading (SR) in promoting reading engagement. It provides a thematic analysis of focus groups with students and teachers at a Swedish upper-secondary school who participated in an ...
Anders Ohlsson +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Piecewise Interpretable Hilbert Spaces
Heavily revised version.
Chevalier, Alexis, Hrushovski, Ehud
openaire +2 more sources
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

