Economic Regulation: Recentralisation of Power or Improved Quality of Regulation? [PDF]
The October 2009 Government Statement on Economic Regulation proposes a number of sensible reforms that are likely to improve regulatory performance in energy, airports, telecommunications, postal services and transport. However, the Government Statement
PAUL K. GORECKI
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Culture, context and crisis: understanding community engagement in Ghana's Ashanti and Northern regions amid COVID-19 - a qualitative study. [PDF]
BMJ Public HealthIssahaku GR +4 more
europepmc +1 more source
Accounting harmonisation: a new strategy vis-a-vis international harmonisation. Communication from the Commission. COM (95) 508 final, 14 November 1995 [PDF]
, 1995 core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Evaluating co-design processes used in the development of healthcare interventions in residential aged care: a scoping review. [PDF]
J Public Health (Oxf)Westworth SE, Lu A, Long KM, Andrew NE.
europepmc +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Nutrition and Hydration at the End of Life in Intensive Care and General End-of-Life Care Settings: Balancing Clinical Evidence, Patient-Centered Care, and Ethical and Legal Principles-A Narrative Review. [PDF]
NutrientsStoian M +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
'Pretty devastating': exploring horse owner and veterinarian lived experiences of the equine Hendra virus. [PDF]
Front Vet SciWhite J +8 more
europepmc +1 more source