Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Interpersonal and intrapersonal leadership competencies: an interpretative phenomenological analysis on effective leadership strategies. [PDF]
Aquino MKA +6 more
europepmc +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Decentralization and immunization program in a single-party state: the case of the Lao People's Democratic Republic. [PDF]
Viphonephom P, Kounnavong S, Reinharz D.
europepmc +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Interprofessional Collaboration in Primary Healthcare: A Qualitative Study of General Practitioners' and Family and Community Nurses' Perspectives in Italy. [PDF]
Dellafiore F +8 more
europepmc +1 more source
It’s Getting Hot in Here: The SEC’s Regulation of Climate Change Shareholder Proposals Under the Ordinary Business Exception [PDF]
Choi, Sung Ho (Danny)
core +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Double Burden of Financial Constraints and Stigma with Isolation of Families of Bipolar Mood Disorder Patients: A Constructivist Grounded Theory Analysis from Tamil Nadu, India. [PDF]
Kala VS +4 more
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source

