The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Lessons Learned From AI-Assisted Guideline Generation in Parastomal Hernia Repair. [PDF]
Śmietański M, Zamkowski M, Tyszka K.
europepmc +1 more source
The Direct Interpretation of the Fast Vital Capacity Record [PDF]
openaire +2 more sources
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Nationwide trends in dementia subtypes and in-hospital mortality among hospitalizations with type 2 diabetes in Spain, 2021-2024: A focus on sex disparities. [PDF]
Cuadrado-Corrales N +8 more
europepmc +1 more source
An instruction for direct interpretation of LZ77-compressed programs [PDF]
openaire +2 more sources
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Enhancing postmortem diagnostics: over a decade of ISO 17020 accreditation and guidelines implementation in forensic pathology. [PDF]
Van Den Bogaert W +4 more
europepmc +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Understanding the contexts and mechanisms that drive high-quality maternity care outcomes within organisations: generating 11 initial programme theories as phase 1 of a realist review. [PDF]
Feeley C +11 more
europepmc +1 more source

