Results 131 to 140 of about 309,034 (308)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
, 1993 Ruby is a relational calculus for designing digital circuits. This document is a guide to the Ruby interpreter, which allows a special class of $quot;implementable$quot; Ruby programs to be executed.
Hutton, Graham
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Development of a relational database management system
Journal of Computer Science and Technology, 2003 The studies of Relational Data Base Management Systems and Databases constitute nowadays a main tren of investigation in large businesses and universities of the entire world.
Anabel Natalia Ruiz +2 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
ŞiHABUDDiN es-SiVASi: HAYATI VE iLMi ŞAHSiYETi
Cumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2005 Şihabuddin es-Sivasi, Anadolu'nun siyasi, iktisadi ve kültürel bakımdan oldukça hareketli. bir döneminde yetişmiş önemli simalardan biridir. Sivas'ta başladığı ilmi hayatını Ayasluğ yani, bugünkü !zmir iline bağ lı Selçuk ilçesinde noktalamıştır ...
Bahattin DARTMA
doaj
Chinese commemorative practices in an English graveyard – observations on the Elswick gravestones
Built HeritageThis paper explores the contemporary use, for commemorative purposes, of Chinese heritage situated outside of China, in the built environment of Newcastle-upon-Tyne (United Kingdom).
Bruce Davenport, Yuan Zhang, Andrew Law
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source