Results 101 to 110 of about 4,680,570 (295)

A critical analysis of interpretive research studies in cooperative education and internships [PDF]

open access: yes, 2009
Much research in co-op has utilized a quantitative or experimental approach within a positivist paradigm. Here we present a critical analysis of interpretive/qualitative studies in terms of output, diversity, quality, along with an overview of the topics
Kalnins, Tatiana   +2 more
core  

Interpretive use: translating intensification

open access: yes, 2001
My aim here is to discuss first the fitness of a cognitive theory like RT when approaching the interpretive operations taking place in the translating activity. The basic notion of interpretive resemblance is put forward instead of the traditional one of
López Folgado, Vicente
core   +1 more source

The Analytic Challenge in Interpretive Description

open access: yesInternational Journal of Qualitative Methods, 2004
The past decade has witnessed remarkable evolution within qualitative health research as scholars have moved beyond initial adherence to the specific methods of phenomenology, grounded theory, and ethnography to develop methods more responsive to the ...
Sally Thorne   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Interpretive Rules in Practice

open access: yes, 2019
At its June 2019 plenary session, the Administrative Conference of the United States (ACUS) adopted Recommendation 2019-1, “Agency Guidance Through Interpretive Rules.” The recommendation offers key suggestions for agency practices to bring treatment of ...
Levin, Ronald M., Emerson, Blake
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

DEVELOPING INSTRUMENTALISTS’ INTERPRETIVE FREEDOM THROUGH PEDAGOGICAL SUPPORT IN THEIR PROFESSIONAL STUDIES

open access: yesStudia Universitatis Babeş-Bolyai. Musica
The relevance of the study is determined by the need to develop creative thinking and an individual performance style in view of the dynamics of the academic musical space.
Marharyta MALAKHOVA   +4 more
doaj   +1 more source

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