Results 41 to 50 of about 17,377 (294)
The intonation of information-seeking absolute interrogatives in Madrid Spanish
Estudios de Fonética Experimental, 2020 Romera and Elordieta (2019) and Elordieta and Romera (2020) reported that most information-seeking absolute interrogatives in the variety of Spanish spoken in the Basque Country have a rising-falling circumflex final contour.
Gorka Elordieta, Magdalena Romera
doaj
Question/answer congruence and the semantics of wh-phrases [PDF]
, 2013 This paper is about the semantics of wh-phrases. It is argued that wh-phrases should not be analyzed as indefinites as, for example, Karttunen (1977) and many others have done, but as functional expressions with an indefinite core -their function being ...
Reich, Ingo
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The syntax of orientation shifting: Evidence from English high adverbs [PDF]
, 2014 This paper reviews new data supporting the inclusion of a Speech Act Phrase in the left periphery. Illocutionary and evidential adverbs in English shift orientation from speakers in declarative sentences to addressees in yes-no interrogative sentences ...
Woods, Rebecca
core
Cognitive constraints and island effects [PDF]
, 2010 Competence-based theories of island effects play a central role in generative grammar, yet the graded nature of many syntactic islands has never been properly accounted for.
Ivan A. Sag,, Philip Hofmeister,
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Questions with long-distance dependencies: a usage-based perspective [PDF]
, 2008 Attested questions with long-distance dependencies (e.g., What do you think you’re doing?) tend to be quite stereotypical: the matrix clause usually consists of a WH word, the auxiliary do or did, the pronoun you, and the verb think or say, with no ...
Dabrowska, Ewa
core +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Managing the Moral Implications of Advice in Informal Interaction [PDF]
, 2013 What does advice giving look like among family members? Most conversation analytic research on advice has been in institutional settings, which constrain what speakers can do.
Hepburn, A, Shaw, C
core +1 more source