Results 51 to 60 of about 17,377 (294)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
IF IT WALKS LIKE A PROVERB AND TALKS LIKE A QUESTION
Proverbium, 2013 Although a small number of question-form phrases have been included in standard proverb dictionaries or have been proposed for inclusion in future dictionaries, many of these phrases, although fixed in form, lack the truth-statement function that ...
Heather A. Haas
doaj
Glossa, 2018 Tactile sign languages used by Deafblind signers are most often acquired by signers competent in a visual sign language who can no longer rely on the grammatical system of the visual language as it is, since some of its features are lost due to the loss ...
Alessandra Checchetto +3 more
doaj +2 more sources
'Should conditionals be emergent ...': asyndetic conditionals in English and German as a Challenge to Grammaticalization Research [PDF]
, 2010 The present article examines asyndetic or conjunctionless conditionals in German and English. According to Jespersen’s Model (1940), this construction arose diachronically from a paratactic discourse sequence with a polar interrogative, but more recently
Van den Nest, Daan
core +1 more source
Review of the book Deaf around the World: The impact of language / ed. by Mathur & Napoli [PDF]
, 2012 (first paragraph) Since its advent half a century ago, the field of sign language linguistics has had close ties to education and the empowerment of deaf communities, a union that is fittingly celebrated by Deaf around the world: The impact of language ...
de Vos, Connie, Palfreyman, Nick
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Inferencing, Reanalysis, and the History of the French est-ce que Question
Open Linguistics, 2018 In this paper, I discuss critically the traditional view of reanalysis, taking into account recent debates about the concept. In particular, I argue that the debate about reanalysis tends to conflate two interpretations of reanalysis: reanalysis as a ...
Waltereit Richard
doaj +1 more source
Pro-drop in interrogatives and declaratives.
Linguistik Online, 2019 While there has been a substantial body of research on the asymmetry between main and subordinate clauses in terms of the licensing of pro-drop, potential differences between types of unembedded clause have received much less attention – despite the fact
Federica Cognola, George Walkden
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source