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Interrupted Time Series Analysis in Clinical Research

Annals of Pharmacotherapy, 2003
OBJECTIVE: To demonstrate the usefulness of interrupted time series analysis in clinical trial design. METHODS: A safety data set of electrocardiographic (ECG) information was simulated from actual data that had been collected in a Phase I study. Simulated data on 18 healthy volunteers based on a study performed in a contract research facility were ...
Lloyd K, Matowe   +3 more
openaire   +2 more sources

Healthcare Utilization After Respiratory Tuberculosis: A Controlled Interrupted Time Series Analysis

Clinical Infectious Diseases, 2023
Abstract Background Despite data suggesting elevated morbidity and mortality among people who have survived tuberculosis disease, the impact of respiratory tuberculosis on healthcare utilization in the years following diagnosis and treatment remains unclear.
Kamila, Romanowski   +7 more
openaire   +2 more sources

Trauma team leader and early mortality: An interrupted time series analysis

The American Journal of Emergency Medicine, 2022
The trauma team leader (TTL) is a "model" of a specifically dedicated team leader in the emergency department (ED), but its benefits are uncertain. The primary objective was to assess the impact of the TTL on 72-hour mortality. Secondary objectives included 24-hour mortality and admission delays from the ED.Major trauma admissions (Injury Severity ...
Jennifer, Truchot   +7 more
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Interrupted Time Series Analysis

2019
Interrupted Time Series Analysis develops a comprehensive set of models and methods for drawing causal inferences from time series. Example analyses of social, behavioural, and biomedical time series illustrate a general strategy for building AutoRegressive Integrated Moving Average (ARIMA) impact models. The classic Box-Jenkins-Tiao
David McDowall   +2 more
openaire   +1 more source

Innovating patient care delivery: DSRIP's interrupted time series analysis paradigm

Healthcare, 2019
Adoption of Medicaid Section 1115 waiver is one of the many ways of innovating healthcare delivery system. The Delivery System Reform Incentive Payment (DSRIP) pool, one of the two funding pools of the waiver has four categories viz. infrastructure development, program innovation and redesign, quality improvement reporting and lastly, bringing about ...
Amrita G, Shenoy   +4 more
openaire   +2 more sources

Computer Programs for Interrupted Time Series Analysis: II A Quantitative Evaluation

Multivariate Behavioral Research, 1990
Interrupted time series analysis is a method of analysis for longitudinal experiments involving a sequence of observations on a single dependent variable before and after an intervention. The presence of dependency in the data necessitates the use of computer programs for data analysis. Five recently developed programs are evaluated: BMDP (Dixon, 1985),
J W, Harrop, W F, Velicer
openaire   +3 more sources

Analysis of the physiological stress profile: The interrupted time-series design

Biofeedback and Self-Regulation, 1986
Most research employing physiological stress profiling procedures has relied upon statistical analyses that are flawed in two ways: These analyses typically average the physiological levels observed across a series of observations during any one phase of the profile, thereby ignoring rate of change as a relevant parameter, and the problem of ...
J B, Cooney, J, Clarke, G L, Morris
openaire   +2 more sources

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