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Impact of carbapenem-targeted antimicrobial stewardship interventions: an interrupted time-series analysis

Journal of Hospital Infection, 2023
The development of carbapenem-resistant Gram-negative bacilli (CR-GNB) is largely favoured by indiscriminate and prolonged carbapenem use, which is a significant contributing factor.To evaluate the impact of two carbapenem antibiotic stewardship programme interventions on both carbapenem prescriptions and the clinical isolation rates of CR-GNBs, using ...
H-J, Son   +9 more
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An interrupted time series analysis of parenteral antibiotic use in Colombia

Journal of Clinical Epidemiology, 2003
A University-based hospital in Bogotá, Colombia, developed and implemented an educational intervention to complement a new structured antibiotic order form. This intervention was performed after assessing the appropriateness of the observed antibiotic prescribing practices using a quasi-experimental study.
Adriana, Pérez   +6 more
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Challenges to validity in single‐group interrupted time series analysis

Journal of Evaluation in Clinical Practice, 2016
AbstractRationale, aims and objectivesSingle‐group interrupted time series analysis (ITSA) is a popular evaluation methodology in which a single unit of observation is studied; the outcome variable is serially ordered as a time series, and the intervention is expected to “interrupt” the level and/or trend of the time series, subsequent to its ...
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Graphical Data Analysis on the Circle: Wrap-Around Time Series Plots for (Interrupted) Time Series Designs

Multivariate Behavioral Research, 2014
Many data structures, particularly time series data, are naturally seasonal, cyclical, or otherwise circular. Past graphical methods for time series have focused on linear plots. In this article, we move graphical analysis onto the circle. We focus on 2 particular methods, one old and one new.
Joseph Lee, Rodgers   +2 more
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Robust testing of level changes in interrupted time-series analysis

Journal of Statistical Computation and Simulation, 2006
Ramsey and Ramsey [Ramsey, P.P. and Ramsey, P.H., 2003, Comparing lease-squares lines for testing level changes in interrupted time-series analysis. Journal of Statistical Computation and Simulation, 73, 31–44.] have shown that a composite procedure (CP) can provide accurate tests of level changes in interrupted time-series analysis.
Patricia P. Ramsey, Philip H. Ramsey
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Interrupted Time Series Analysis Techniques in Pharmacovigilance

2013
This thesis considers an approach to evaluate the effectiveness of risk communications for prescription drugs by performing interrupted time series analysis of prescription drug volumes prior to and after the risk communication date. The paper presents methods for detecting change in the presence of autocorrelation and techniques to reduce bias in ...
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Interrupted time-series analysis with brief single-subject data.

Journal of Consulting and Clinical Psychology, 1993
Assessing change with short time-series data is difficult because visual inference is unreliable with such data, and current statistical procedures cannot control Type I error because they underestimate positive autocorrelation. This article describes these problems and shows how they can be solved with a new interrupted time-series analysis procedure (
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Use of Interrupted Time Series Analysis in Evaluating Health Care Quality Improvements

Academic Pediatrics, 2013
Interrupted time series (ITS) analysis is arguably the strongest quasi-experimental research design. ITS is particularly useful when a randomized trial is infeasible or unethical. The approach usually involves constructing a time series of population-level rates for a particular quality improvement focus (eg, rates of attention-deficit/hyperactivity ...
Robert B, Penfold, Fang, Zhang
exaly   +3 more sources

Crisis intervention and the prevention of institutionalization: An interrupted time series analysis

American Journal of Community Psychology, 1978
In the context of the community mental health movement in Illinois, the evolution and development of a crisis intervention program aimed at avoiding state hospitalization and bringing more appropriate and efficacious resources to bear on the difficulties of the individual and/or family is described.
J A, Delaney, E, Seidman, G, Willis
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Statistical methods for meta-analysis of interrupted time series studies

2023
An interrupted time series study is a type of non-randomised study that allows researchers to quantify the immediate and long-term impact of interruptions like public health policies. For example, the impact of a mass media campaign on HIV testing rates.
openaire   +1 more source

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