Results 111 to 120 of about 1,494,547 (346)

Assessing the impact of a restrictive opioid prescribing law in West Virginia

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2021
Background The Opioid Reduction Act (SB 273) took effect in West Virginia in June 2018. This legislation limited ongoing chronic opioid prescriptions to 30 days’ supply, and first-time opioid prescriptions to 7 days’ supply for surgeons and 3 days’ for ...
Cara L. Sedney   +5 more
doaj   +1 more source

Influence of safety warnings on ESA prescribing among dialysis patients using an interrupted time series [PDF]

open access: yes, 2013
BACKGROUND: In March, 2007, a black box warning was issued by the Food and Drug Administration (FDA) to use the lowest possible erythropoiesis-stimulating agents (ESA) doses for treatment of anemia associated with renal disease.
Dejian Lai   +4 more
core   +1 more source

Social distancing to slow the U.S. COVID-19 epidemic: an interrupted time-series analysis

open access: yesmedRxiv, 2020
Background: Social distancing measures to address the U.S. COVID-19 epidemic may have significant health, social, and economic impacts. Objective: To estimate the mean change in state-level COVID-19 epidemic growth before versus after the implementation ...
M. Siedner   +5 more
semanticscholar   +1 more source

Designing Asymmetric Memristive Behavior in Proton Mixed Conductors for Neuromorphic Applications

open access: yesAdvanced Functional Materials, EarlyView.
Protonic devices that couple ionic and electronic transport are demonstrated as bioinspired neuromorphic elements. The devices exhibit rubber‐like asymmetric memristive behavior with slow voltage‐driven conductance increase and rapid relaxation, enabling simplified read–write operation.
Nada H. A. Besisa   +6 more
wiley   +1 more source

Initial impact of COVID-19’s stay-at-home order on motor vehicle traffic and crash patterns in Connecticut: an interrupted time series analysis

open access: yesInjury Prevention, 2020
Introduction Understanding how the COVID-19 pandemic has impacted our health and safety is imperative. This study sought to examine the impact of COVID-19’s stay-at-home order on daily vehicle miles travelled (VMT) and MVCs in Connecticut.
Mitchell L. Doucette   +8 more
semanticscholar   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni   +8 more
wiley   +1 more source

On Measurement and Interpretation of Toughness Behaviour of Carbide Tools [PDF]

open access: yes, 1981
The actual significance of any definition of toughness behaviour of carbide tools depends on the existence of an interrelation between the quality as defined and the occurrence of chipping and premature failure in cutting.
Kals, H.J.J.
core   +2 more sources

Excess mortality during the COVID-19 outbreak in Italy: a two-stage interrupted time-series analysis

open access: yesmedRxiv, 2020
Background: Italy was the first country outside China to experience the impact of the COVID-19 pandemic, which resulted in a significant health burden. This study presents an analysis of the excess mortality across the 107 Italian provinces, stratified ...
M. Scortichini   +8 more
semanticscholar   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Is Democracy Good for the Environment? Quasi-Experimental Evidence from Regime Transitions [PDF]

open access: yes
This paper tests the hypothesis that democratisation is conducive to less environmental depletion due to human activity. Using Interrupted Time Series (ITS) design for a panel of 47 transition countries and two indexes of pollution, CO2 emissions and ...
Laura Policardo
core  

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