Results 131 to 140 of about 94,628 (298)

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Suicide prevention plans and suicide mortality in Spain, 2010-2023: an interrupted time-series analysis

Frontiers in Psychiatry
BackgroundThe serious problem posed by suicide deaths has led to increased awareness and the implementation of prevention plans in a large number of countries worldwide. The main aim of this study is to determine the relationship between the variation in
Gerardo Flórez, Gerardo Flórez, Ashkan Espandian, Teresa Seoane-Pillado, José Manuel Gerpe, Rocío Villa, Antonio Serrano-García, Pilar Saiz, Pilar Saiz, Pilar Saiz, Pilar Saiz, Pilar Saiz   +11 more
doaj   +1 more source

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

Advanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang, Kangning Tan, Zihan He, Hongsen Pang, Yanjie Wang, Hongbin Fang, Jian Xu   +6 more
wiley   +1 more source

Interrupted time series analysis of monthly drug consumption measured by DDD/1000P in: (E) Antimicrobials. [PDF]

Interrupted time series analysis of monthly drug consumption measured by DDD/1000P in: (E) Antimicrobials.
Nguyen Dang Tu Le (10024031), Minh-Anh Le-Dang (17817332), Hien Pham Thu (17817341), Luyen Pham Dinh (17817335), Dinh Thanh Le (17817344), Hai-Yen Nguyen-Thi (9963037), Danh Le Ngoc (17817338)   +6 more
core   +1 more source

Impact of the two-dose varicella vaccination recommendation program and surveillance optimization on epidemiological trends in a megacity in China

Human Vaccines & Immunotherapeutics
To assess the impact of implementing a two-dose varicella vaccine (VarV) immunization recommendation program on the incidence of varicella in Chongqing, China. Monthly reported varicella cases from 2011 to 2023 were extracted from the National Notifiable
Yang Liu, Jiangning Xu, Hang Zhang, Jiawei Xu, Yuanyuan Zhang, Qing Wang, Hengqing Ji, Chunbei Zhou, Ning Yao   +8 more
doaj   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Deciphering the Dynamic Balance Between Solvation Strength and Polysulfides Reaction Heterogeneity in Practical Lithium‐Sulfur Batteries

Advanced Science, EarlyView.
A weakly solvating fluorinated cosolvent (1200ET) enables precise solvation‐power regulation in Li–S batteries, decoupling interfacial stabilization from sulfur redox kinetics. This approach suppresses polysulfide dissolution while preserving reaction kinetics, leading to a stable Li metal interface and high‐energy multilayer pouch cells, revealing a ...
Huidong Dai, Pranathi Garlapati, Srinidi Badhrinathan, Luisa Gomes, Tongtai Ji, Dominik Wierzbicki, Yonghua Du, Neville Pavri, Sanjeev Mukerjee, Gaind P. Pandey   +9 more
wiley   +1 more source

V2CTx MXene as a Sacrificial Promoter for NiFe Catalyst for Anion Exchange Membrane Electrolyzers

Advanced Science, EarlyView.
These findings demonstrate that V2CTx functions beyond passive conductive support as an active electronic participant whose structural legacy sustains durable performance even after vanadium leaching in Anion Exchange Membrane (AEM) Electrolysers. ABSTRACT Nickel‐iron layered double hydroxides (NiFe‐LDH) show excellent activity, their poor conductivity
Bastian Schmiedecke, Can Kaplan, Karuppasamy Dharmaraj, Axel Zuber, Merve Buldu‐Aktürk, Ningjun Chen, Mailis Lounasvuori, Xuyun Guo, Valeria Nicolosi, Thorsten Schultz, Norbert Koch, Johanna Rosen, Michelle P. Browne   +12 more
wiley   +1 more source

Segmented Regression in an Interrupted Time Series Study Design

Anesthesia & Analgesia, 2021
Schober, Patrick, Vetter, Thomas R.
openaire   +3 more sources