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Interrupted Time Series Analysis Techniques in Pharmacovigilance [PDF]
, 2013 This thesis considers an approach to evaluate the effectiveness of risk communications for prescription drugs by performing interrupted time series analysis of prescription drug volumes prior to and after the risk communication date. The paper presents methods for detecting change in the presence of autocorrelation and techniques to reduce bias in ...
Prendergast, Tim
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Clarifying the interrupted time series study design
BMJ Quality & Safety, 2015We believe that the use of the term ‘interrupted time series study’ to describe two reports from this year’s February issue of BMJ Quality & Safety is potentially misleading.1 ,2 Putting aside the merits of the studies themselves, we would like to clarify what the interrupted time series design entails to promote a productive conversation of its ...
Theodore, Svoronos, Atle, Fretheim
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Interrupted Time Series Analysis in Clinical Research
Annals of Pharmacotherapy, 2003OBJECTIVE: To demonstrate the usefulness of interrupted time series analysis in clinical trial design. METHODS: A safety data set of electrocardiographic (ECG) information was simulated from actual data that had been collected in a ...
Lloyd K, Matowe +3 more
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Interrupted Time Series Analysis
2019Interrupted Time Series Analysis develops a comprehensive set of models and methods for drawing causal inferences from time series. Example analyses of social, behavioural, and biomedical time series illustrate a general strategy for building AutoRegressive Integrated Moving Average (ARIMA) impact models. The classic Box-Jenkins-Tiao
David McDowall +2 more
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A Comparison of Alternative Approaches to the Analysis of Interrupted Time-Series
Multivariate Behavioral Research, 1985Computer generated data representative of 26 ARIMA models was used to compare the results of interrupted time-series analysis using: (1) the known model identification, (2) an assumed (1, 0, 0) model, and (3) an assumed (3, 0, 0) model as an approximation to the General Transformation approach.
J W, Harrop, W F, Velicer
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Current Rheumatology Reports, 2020
The propose of this viewpoint is to improve or facilitate the clinical decision-making in the management/treatment strategies of arthritis patients through knowing, understanding, and having access to an interactive process allowing assessment of the patient disease outcome in the future.In recent years, the time series (TS) concept has become the ...
Hossein Bonakdari +2 more
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The propose of this viewpoint is to improve or facilitate the clinical decision-making in the management/treatment strategies of arthritis patients through knowing, understanding, and having access to an interactive process allowing assessment of the patient disease outcome in the future.In recent years, the time series (TS) concept has become the ...
Hossein Bonakdari +2 more
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TVZ - Verpleegkunde in praktijk en wetenschap, 2021
J. M. Maaskant, B. J. Laan
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J. M. Maaskant, B. J. Laan
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Analysis of the physiological stress profile: The interrupted time-series design
Biofeedback and Self-Regulation, 1986Most research employing physiological stress profiling procedures has relied upon statistical analyses that are flawed in two ways: These analyses typically average the physiological levels observed across a series of observations during any one phase of the profile, thereby ignoring rate of change as a relevant parameter, and the problem of ...
J B, Cooney, J, Clarke, G L, Morris
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An interrupted time series analysis of parenteral antibiotic use in Colombia
Journal of Clinical Epidemiology, 2003A University-based hospital in Bogotá, Colombia, developed and implemented an educational intervention to complement a new structured antibiotic order form. This intervention was performed after assessing the appropriateness of the observed antibiotic prescribing practices using a quasi-experimental study.
Adriana, Pérez +6 more
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