Results 61 to 70 of about 132,124 (298)

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

Feshbach spectroscopy and dual-species Bose-Einstein condensation of $^{23}\mathrm{Na}-$$^{39}\mathrm{K}$ mixtures

open access: yes, 2018
We present measurements of interspecies Feshbach resonances and subsequent creation of dual-species Bose-Einstein condensates of $^{23}\mathrm{Na}$ and $^{39}\mathrm{K}$. We prepare both optically trapped ensembles in the spin state $\left|f = 1,m_{f}=-1\
Gempel, Matthias W.   +6 more
core   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang   +8 more
wiley   +1 more source

Adaptation of Human Influenza Viruses to Swine

open access: yesFrontiers in Veterinary Science, 2019
A large diversity of influenza A viruses (IAV) within the H1N1/N2 and H3N2 subtypes circulates in pigs globally, with different lineages predominating in specific regions of the globe.
Daniela S. Rajao   +2 more
doaj   +1 more source

Bright solitons and soliton trains in a fermion-fermion mixture

open access: yes, 2006
We use a time-dependent dynamical mean-field-hydrodynamic model to predict and study bright solitons in a degenerate fermion-fermion mixture in a quasi-one-dimensional cigar-shaped geometry using variational and numerical methods.
297   +25 more
core   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

Three-dimensional quantum phase diagram of the exact ground states of a mixture of two species of spin-1 Bose gases with interspecies spin exchange

open access: yes, 2011
We find nearly all the exact ground states of a mixture of two species of spin-1 atoms with both interspecies and intraspecies spin exchanges in absence of a magnetic field.
Ge, Li, Shi, Yu
core   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

open access: yesAdvanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza   +19 more
wiley   +1 more source

Messages from the Underground: Interspecies Memory in Times of the Climate Change

open access: yes452ºF, 2019
In times of climate change, the citizens of Málaga (Spain) must consider how to respond to both the longer droughts and the torrential rain falls that pose serious threats to local agriculture. In this context, the non-profit group Ecoherencia researches
Katarzyna Olga Beilin
doaj  

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