Results 101 to 110 of about 3,668,149 (172)

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Direct interspecies electron transfer enables anaerobic oxidation of sulfide to elemental sulfur coupled with CO₂-reducing methanogenesis. [PDF]

iScience, 2023
Jung H, Yu H, Lee C.
europepmc   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Biochar Facilitated Direct Interspecies Electron Transfer in Anaerobic Digestion to Alleviate Antibiotics Inhibition and Enhance Methanogenesis: A Review. [PDF]

Int J Environ Res Public Health, 2023
Zhang K, Deng Y, Liu Z, Feng Y, Hu C, Wang Z.   +5 more
europepmc   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

The TRPM2–PARP‐1 Axis Involvement in Bisphenol A and Nonylphenol‐Induced Ferroptosis in Trigeminal Ganglion Cells

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3660-3674, October 2026.
ABSTRACT Environmental contaminants like bisphenol A (BPA) and nonylphenol (NP) are recognized neurotoxicants; however, the molecular mechanisms underlying their impact on sensory ganglia, specifically the trigeminal ganglion (TG), remain critically underexplored.
Betül Yazğan, Musa Tatar, Yener Yazğan, Kıymet Kübra Tüfekci   +3 more
wiley   +1 more source

Interspecies electron transfer stimulating approaches in anaerobic digestion process: recent advancements, challenges, and future perspectives

Environmental Systems Research
Anaerobic digestion (AD) is a biological process of converting complex organic matter into biogas (methane) and digestate in the absence of oxygen by microorganisms.
Wondimu Elias Worajo, Fekadu Fanjana Falta, Selemon Thomas Fakana   +2 more
doaj   +1 more source

Review on Mechanisms of Iron Accelerants and Their Effects on Anaerobic Digestion

Agriculture
Anaerobic digestion is an important technology for energy recovery from organic waste. However, methanogenesis is restricted by some barriers, such as the low-speed bottleneck of interspecies electron transfer (IET), the low hydrogen partial pressure ...
Han Wang, Wanli Zhang, Wanli Xing, Rundong Li   +3 more
doaj   +1 more source

Syntrophic Growth with Direct Interspecies Electron Transfer as the Primary Mechanism for Energy Exchange

, 2013
Direct interspecies electron transfer (DIET) through biological electrical connections is an alternative to interspecies H-2 transfer as a mechanism for electron exchange in syntrophic cultures.
Aklujkar, Muktak, Summers, Zarath M, Summers, Zarath M., Malvankar, Nikhil, Shrestha, Pravin Malla, Liu, Fanghua, Flores, Dan Carlo, Lovley, Derek R., Shrestha, Minita, Rotaru, Amelia-Elena; id_orcid, Lovley, Derek R, Rotaru, Amelia-Elena   +11 more
core   +1 more source

Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng, Yuanyuan Shen, Ying Sun, Lu Lu, Chongkui Sun   +4 more
wiley   +1 more source