Results 91 to 100 of about 6,704,120 (325)

The Human Gut Microbiome is Structured to Optimize Molecular Interaction Networks

Computational and Structural Biotechnology Journal, 2019
Microbiome studies estimate the functions of bacterial flora in situ on the basis of species composition and gene function; however, estimation of interspecies interaction networks is challenging.
Yiwei Ling, Yu Watanabe, Shujiro Okuda
doaj   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Interspecific-interaction-between-Microtus-ochrogaster-and-Microtus-pennsylvanicus-Data-Records

, 2022
Monthly data records of effects of interspecific interactions on population densities of Microtus ochrogaster and Microtus ...
Getz, Lowell L
core  

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Phylogenetic relatedness, ecological strategy, and stress determine interspecific interactions within a salt marsh community

, 2017
Species interactions in nature can be positive or negative. The stress gradient hypothesis (SGH) states that the strength of positive interactions increases with increasing stress.
Wang, Bingchen, Qi, Longbin, Zhang, Liwen, Zhang, LW(reprint author), Yantai Institute of Coastal Zone ResearchChinese Academy of SciencesYantaiChina. lwzhang@yic.ac.cn   +3 more
core   +1 more source

Meta‐Analysis of the Effects of Forest Fragmentation on Interspecific Interactions

Conservation Biology, 2014
Abstract Forest fragmentation dramatically alters species persistence and distribution and affects many ecological interactions among species. Recent studies suggest that mutualisms, such as pollination and seed dispersal, are more sensitive to the negative effects of forest fragmentation than antagonisms, such as predation or ...
Magrach, Ainhoa, Laurance, William F., Larrinaga, Asier R., Santamaria, Luis   +3 more
openaire   +4 more sources

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

Advanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv, Yi Liu, Ning Xu, Xiao Zhang, Yaming Yang, Chengyao Li, Hanhai Mao, Mingyuan Liu, Xiaolei Liu   +8 more
wiley   +1 more source

Different Non-Saccharomyces Yeast Species Stimulate Nutrient Consumption in S. cerevisiae Mixed Cultures

Frontiers in Microbiology, 2017
The growing interest of the winemaking industry on the use of non-Saccharomyces starters has prompted several studies about the physiological features of this diverse group of microorganisms.
Jose A. Curiel, Pilar Morales, Ramon Gonzalez, Jordi Tronchoni   +3 more
doaj   +1 more source

Interspecific interactions and premating reproductive isolation [PDF]

, 2008
AbstractTwo species can interact in several ways: there may occur interspecific competition or aggression, the two species may hybridize or they may interact indirectly through different predator-prey interactions. One consequence of these interactions is the evolution of premating reproductive isolation between the two species.
Tynkkynen, Katja, Kotiaho, Janne Sakari, Svensson, Erik I.   +2 more
openaire   +2 more sources