Results 81 to 90 of about 137,492 (222)

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

PPNID : a reference database and molecular identification pipeline for plant-parasitic nematodes [PDF]

, 2020
Motivation: The phylum Nematoda comprises the most cosmopolitan and abundant metazoans on Earth and plant-parasitic nematodes represent one of the most significant nematode groups, causing severe losses in agriculture.
Bert, Wim, Braun-Miyara, Sigal, Bucki, Patricia, Karssen, Gerrit, Qing, Xue, Wang, Meng   +5 more
core   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Genome size variation among and within Camellia species by using flow cytometric analysis. [PDF]

PLoS ONE, 2013
BACKGROUND: The genus Camellia, belonging to the family Theaceae, is economically important group in flowering plants. Frequent interspecific hybridization together with polyploidization has made them become taxonomically "difficult taxa".
Hui Huang, Yan Tong, Qun-Jie Zhang, Li-Zhi Gao   +3 more
doaj   +1 more source

Phylogenetic relationships in Betula (Betulaceae) based on AFLP markers [PDF]

, 2008
The genus Betula comprises various species in boreal and temperate climate zones of the Northern Hemisphere. The taxonomy of Betula is controversial and complicated by parallel evolution of morphological traits, polyploidization events, and extensive ...
Gilissen, L.J.W.J., Koopman, W.J.M., Schenk, M.F., Smulders, M.J.M., Thienpont, C.N.   +4 more
core   +2 more sources

Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury

Advanced Science, EarlyView.
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie, Gulimire Yilihan, Qiong Chen, Dachuan Lin, Zhen Liu, Mengyi Yuan, Yujia Wang, Haoteng Xu, Weishang Zhou, Wanxin Gong, Yueer Li, Chen Peng, Tong Yang, Peng Gao, Qing Liu, Xin‐Hua Feng, Mu Xiao, Chao Jiang   +17 more
wiley   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Does a whole plant conservation gradient exist within a subtropical broadleaved evergreen forest?

Frontiers in Plant Science
The coordination between leaf and root traits is crucial for plants to synchronize their strategies for acquiring and utilizing above- and belowground resources.
Ailian Fan, Ailian Fan, Xue Wang, Xue Wang, Xiaojun Yan, Xiaojun Yan, Tingting Chen, Tingting Chen, Qi Jiang, Qi Jiang, Linqiao Jia, Linqiao Jia, Weiwei Wang, Weiwei Wang, Decheng Xiong, Decheng Xiong, Jinxue Huang, Jinxue Huang, Guangshui Chen, Guangshui Chen   +19 more
doaj   +1 more source

Spatial patterns of ectomycorrhizal assemblages in a monospecific forest in relation to host tree genotype

Frontiers in Plant Science, 2013
Ectomycorrhizas (EcM) are important for soil exploration and thereby may shape belowground interactions of roots. We investigated the composition and spatial structures of EcM assemblages in relation to host genotype in an old-growth, monospecific beech (
Christa eLang, Christa eLang, Reiner eFinkeldey, Andrea ePolle   +3 more
doaj   +1 more source

Leaf functional trait variation in a humid temperate forest, and relationships with juvenile tree light requirements [PDF]

PeerJ, 2019
The species-rich arborescent assemblages of humid tropical forests encompass much of the known range of the leaf economics spectrum, often including >20-fold variation in leaf lifespan.
Christopher H. Lusk
doaj   +2 more sources